{"id":"W1946521533","doi":"10.1111/j.1600-065x.2010.00945.x","title":"B‐cell targeted therapies in human autoimmune diseases: an updated perspective","year":2010,"lang":"en","type":"review","venue":"Immunological Reviews","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":228,"is_retracted":false,"has_abstract":true,"ca_institutions":"Discovery Centre","funders":"","keywords":"Immunology; Biology; B-cell activating factor; B cell; Context (archaeology); Autoimmunity; Acquired immune system; Immune system; Autoimmune disease; Antibody","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001797542,0.0008984717,0.001466997,0.00216568,0.0003262488,0.001772683,0.0008187095,0.002022777,0.004792572],"category_scores_gemma":[0.001434108,0.0002768101,0.000502206,0.002049137,0.0008102275,0.002603156,0.0009059983,0.004197468,0.002081757],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007087381,"about_ca_system_score_gemma":0.001138677,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008609384,"about_ca_topic_score_gemma":0.00207219,"domain_scores_codex":[0.9995586,0.0001093404,0.00006919224,0.00005080925,0.000170678,0.00004139628],"domain_scores_gemma":[0.9988876,0.0004578452,0.0001183938,0.00003668489,0.0003564258,0.0001430684],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002510394,0.0001635127,0.0003320212,0.007745261,0.0001385671,0.0003543874,0.0001276914,0.0003523512,0.004191425,0.006130495,0.1235557,0.8566575],"study_design_scores_gemma":[0.00003165278,0.0001537538,0.0004883766,0.001867836,0.00008576469,0.0008414965,0.00005185536,0.00006992464,0.0002560175,0.001298785,0.9948396,0.00001496846],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001349983,0.9945204,0.0002218898,0.002473272,0.001539687,0.000004417099,0.00002014411,0.0000159277,0.001069323],"genre_scores_gemma":[0.0007470529,0.9926019,0.0005277498,0.002339066,0.002867655,0.000009073092,0.00004006777,0.000004577656,0.0008628888],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.004792572,"threshold_uncertainty_score":0.01603276,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04009859706010281,"score_gpt":0.3271288287554941,"score_spread":0.2870302316953913,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}