{"id":"W1947394714","doi":"10.1128/aac.02068-15","title":"Activity of Tobramycin against Cystic Fibrosis Isolates of Burkholderia cepacia Complex Grown as Biofilms","year":2015,"lang":"en","type":"article","venue":"Antimicrobial Agents and Chemotherapy","topic":"Cystic Fibrosis Research Advances","field":"Medicine","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Michael's Hospital; Child and Family Research Institute; Hospital for Sick Children; University of British Columbia; SickKids Foundation; University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Tobramycin; Burkholderia cepacia complex; Burkholderia; Burkholderia cenocepacia; Microbiology; Sputum; Biofilm; Cystic fibrosis; Biology; Pseudomonas aeruginosa; Antibiotics; Chemistry; Bacteria; Medicine; Gentamicin; Pathology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001159515,0.0002686982,0.0002888371,0.0001307774,0.0001463926,0.0001979045,0.000173829,0.0003041507,0.0005188539],"category_scores_gemma":[0.0002303714,0.0001140581,0.0001937156,0.0001156179,0.0001022231,0.0001626941,0.0002236585,0.0003234531,0.0001230949],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001306338,"about_ca_system_score_gemma":0.0001822927,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002123483,"about_ca_topic_score_gemma":0.002662799,"domain_scores_codex":[0.999861,0.00003945423,0.00001170986,0.00002408052,0.00003843753,0.00002539464],"domain_scores_gemma":[0.9998657,0.00003442191,0.00002712932,0.00001527878,0.00003478116,0.00002263884],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007641878,0.00002901312,0.0001860776,0.00002566516,0.000003362147,0.00001121058,0.00001578656,0.00005031525,0.9988575,0.000008759129,0.0000121081,0.0007238183],"study_design_scores_gemma":[0.00002352612,0.001221706,0.01097082,0.00001727501,0.00001478504,0.0001448315,0.00007280581,0.001048077,0.9856585,0.00001837812,0.0008026225,0.000006796399],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9979532,0.0008174497,0.0005647734,0.00005226389,0.00001133268,0.00002006988,0.0001040228,0.00001287482,0.0004639541],"genre_scores_gemma":[0.9964904,0.0007249279,0.001979565,0.00003045806,0.000007219522,0.00002354319,0.0001601868,0.000006220323,0.0005773621],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002123483,"threshold_uncertainty_score":0.004222214,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03256627796251856,"score_gpt":0.3090915687677367,"score_spread":0.2765252908052182,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}