{"id":"W1947824150","doi":"10.1016/j.yjmcc.2015.09.015","title":"CTGF knockout does not affect cardiac hypertrophy and fibrosis formation upon chronic pressure overload","year":2015,"lang":"en","type":"article","venue":"Journal of Molecular and Cellular Cardiology","topic":"Connective Tissue Growth Factor Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":48,"is_retracted":false,"has_abstract":false,"ca_institutions":"Western University","funders":"Nederlandse Federatie van Universitair Medische Centra; ZonMw; California Institute for Regenerative Medicine","keywords":"CTGF; Pressure overload; Fibrosis; Connective tissue; Internal medicine; Endocrinology; Cardiac fibrosis; Growth factor; Knockout mouse; Matricellular protein; Sirius Red; Medicine; Conditional gene knockout; Fibronectin; Extracellular matrix; Muscle hypertrophy; Biology; Pathology; Cell biology; Phenotype; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006039522,0.0001947036,0.00044542,0.0001076609,0.00006058927,0.00003941676,0.0001432861,0.0002309955,0.000003690204],"category_scores_gemma":[0.0002126951,0.0001487924,0.0002294359,0.00006008669,0.0001109951,0.00001950214,0.0001803848,0.0002292238,0.0000021269],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003794236,"about_ca_system_score_gemma":0.0001194763,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000141659,"about_ca_topic_score_gemma":0.00000322899,"domain_scores_codex":[0.9984488,0.0004743106,0.000274703,0.0002619366,0.0002545074,0.0002857397],"domain_scores_gemma":[0.9990699,0.00003182527,0.0001609194,0.000244562,0.0002610621,0.0002317073],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002956509,0.000009561908,0.0022788,0.00006228415,0.0003584493,0.00008434262,0.00006429391,0.0001184222,0.9931214,0.00003893894,0.0003414731,0.003226374],"study_design_scores_gemma":[0.001374675,0.001974589,0.002397487,0.00002457499,0.0002269494,0.0004361355,0.000133534,0.00006549889,0.9496605,0.0001079314,0.04335478,0.0002433221],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9581239,0.037285,0.003742754,0.0001622044,0.0002677601,0.0001918061,0.00002576844,0.000004652135,0.0001962217],"genre_scores_gemma":[0.9982787,0.0009133037,0.0001340319,0.00004032808,0.0004899109,0.000007124427,0.00002328724,0.00002302614,0.00009029832],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04346089,"threshold_uncertainty_score":0.6067577,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01224781600042029,"score_gpt":0.2471769059357366,"score_spread":0.2349290899353163,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}