{"id":"W1948441138","doi":"10.4049/jimmunol.181.10.6859","title":"Dendritic Cell Differentiation Induced by a Self-Peptide Derived from Apolipoprotein E","year":2008,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Immune Response and Inflammation","field":"Immunology and Microbiology","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity; Canadian Institutes of Health Research; Robarts Clinical Trials; Western University","funders":"Howard Hughes Medical Institute","keywords":"CD86; Cell biology; CD11c; Dendritic cell; Biology; T cell; Immune system; Antigen-presenting cell; Splenocyte; Signal transduction; CD40; Follicular dendritic cells; Flow cytometry; p38 mitogen-activated protein kinases; Cytotoxic T cell; Molecular biology; Immunology; MAPK/ERK pathway; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008268721,0.0002036141,0.0001689682,0.0001431423,0.00009605697,0.0001447478,0.00007961613,0.0001677996,0.0005919724],"category_scores_gemma":[0.00009204374,0.00008702079,0.0001369012,0.00009593733,0.0001238568,0.00006541315,0.0001294132,0.0005404521,0.0002812559],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001554338,"about_ca_system_score_gemma":0.0001533295,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002577016,"about_ca_topic_score_gemma":0.0003349718,"domain_scores_codex":[0.9999187,0.00001110354,0.000007306674,0.00001252333,0.00002029312,0.00003013148],"domain_scores_gemma":[0.9999298,0.0000129664,0.00001529433,0.000008302583,0.000009654865,0.00002402616],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000143225,0.00004119899,0.0001975265,0.00002430676,0.000001482408,0.0001253464,0.00001032123,0.00001882346,0.998478,0.00003351762,0.00003280078,0.0008934971],"study_design_scores_gemma":[0.00007391036,0.0003641899,0.009749491,0.00001147455,0.00001090812,0.0004295622,0.00003153325,0.0005658887,0.9864351,0.0000782443,0.002245991,0.000003735566],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9975975,0.0004147208,0.0005465572,0.00004751332,0.00002828877,0.00002098964,0.0001499803,0.00002810583,0.001166289],"genre_scores_gemma":[0.9959858,0.000576974,0.001071175,0.00008773772,0.00001392433,0.00003555227,0.0003863493,0.000009313398,0.001833237],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005919724,"threshold_uncertainty_score":0.001980305,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009279927540141454,"score_gpt":0.2010288266517946,"score_spread":0.1917488991116531,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}