{"id":"W1948806867","doi":"10.1002/cbic.201500248","title":"PNA Molecular Beacons Assembled by Post‐Synthetic Click Chemistry Functionalization","year":2015,"lang":"en","type":"article","venue":"ChemBioChem","topic":"Advanced biosensing and bioanalysis techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Click chemistry; Surface modification; Molecular beacon; Chemistry; Posttranslational modification; Combinatorial chemistry; Nanotechnology; Organic chemistry; Biochemistry; Materials science; Enzyme","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004495412,0.0004577573,0.0002398789,0.0002420897,0.0001607751,0.0002430071,0.0003331619,0.0003611592,0.001497287],"category_scores_gemma":[0.0004305579,0.0003072476,0.0002330961,0.0001727688,0.0002619295,0.0003625324,0.0003026723,0.0007639523,0.0008417118],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002287604,"about_ca_system_score_gemma":0.0002111275,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000214508,"about_ca_topic_score_gemma":0.0002630298,"domain_scores_codex":[0.9997321,0.00004482922,0.00002109039,0.00007131698,0.00008489536,0.00004575858],"domain_scores_gemma":[0.9998367,0.00004126072,0.00003949777,0.00001766988,0.00003706405,0.00002789759],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002102546,0.00001066589,0.00003297659,0.00002815375,0.000002070708,0.00002638011,0.00001338827,0.0000785096,0.9967874,0.0002242181,0.00004468268,0.002730558],"study_design_scores_gemma":[0.000003694325,0.0000476872,0.000160706,0.000001473964,0.000003010735,0.00006392887,0.000002521941,0.0004886465,0.9971528,0.00003966244,0.002032968,0.000002897006],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7480906,0.003690402,0.2395038,0.0003592608,0.000230923,0.000296359,0.000453737,0.001689918,0.005685121],"genre_scores_gemma":[0.8884413,0.001673211,0.1011271,0.0002169604,0.00006095537,0.0003320418,0.0007248504,0.0001402971,0.007283136],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001497287,"threshold_uncertainty_score":0.005008936,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00889000343156363,"score_gpt":0.2525474345993385,"score_spread":0.2436574311677749,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}