{"id":"W1948806867","doi":"10.1002/cbic.201500248","title":"PNA Molecular Beacons Assembled by Post‐Synthetic Click Chemistry Functionalization","year":2015,"lang":"en","type":"article","venue":"ChemBioChem","topic":"Advanced biosensing and bioanalysis techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Click chemistry; Surface modification; Molecular beacon; Chemistry; Posttranslational modification; Combinatorial chemistry; Nanotechnology; Organic chemistry; Biochemistry; Materials science; Enzyme","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001921363,0.0002620338,0.0002051133,0.00002881213,0.00006776921,0.00003781385,0.000203001,0.0003154119,0.00001135587],"category_scores_gemma":[0.0002523486,0.000258948,0.0001568865,0.000180575,0.00009376578,0.00000633195,0.000111062,0.0001140056,0.00001509958],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005131642,"about_ca_system_score_gemma":0.0001098204,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001178131,"about_ca_topic_score_gemma":0.00000172031,"domain_scores_codex":[0.9986038,0.0000343106,0.0002599571,0.0005621474,0.0002470621,0.0002927041],"domain_scores_gemma":[0.998754,0.000007633977,0.0001332103,0.0005256853,0.000369938,0.0002095705],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004917666,0.00009916004,0.00007009505,0.00001379732,0.00006639308,0.000002963087,0.000007803284,0.000005761749,0.9833742,0.0000225576,0.01548451,0.0008036121],"study_design_scores_gemma":[0.0003972324,0.00008840297,0.00001030273,0.00001366987,0.00005521152,0.00003181586,0.00007874928,0.00008508418,0.9588324,0.0001057463,0.03997612,0.0003251994],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9860895,0.001067971,0.006207488,0.000496097,0.00006733317,0.0001364188,0.00003278779,0.0001247204,0.005777727],"genre_scores_gemma":[0.9937619,0.00005515826,0.001440138,0.0006219069,0.0001610615,0.00001977598,0.00131771,0.000042104,0.002580234],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02454171,"threshold_uncertainty_score":0.9999863,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00889000343156363,"score_gpt":0.2525474345993385,"score_spread":0.2436574311677749,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}