{"id":"W1949237644","doi":"10.1371/journal.pgen.1005573","title":"Parent-of-Origin Effects of the APOB Gene on Adiposity in Young Adults","year":2015,"lang":"en","type":"article","venue":"PLoS Genetics","topic":"Genetic Associations and Epidemiology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre Hospitalier Universitaire de Sherbrooke; Université de Sherbrooke","funders":"National Institute of Environmental Health Sciences; National Heart, Lung, and Blood Institute; National Institutes of Health; National Institute on Drug Abuse; Internationale Stichting Alzheimer Onderzoek; Centre for Medical Systems Biology; National Research Foundation Singapore; Hersenstichting; National Center for Advancing Translational Sciences; National Human Genome Research Institute; Nederlandse Organisatie voor Wetenschappelijk Onderzoek; Russian Foundation for Basic Research; National Institute of Diabetes and Digestive and Kidney Diseases; ZonMw; National Cancer Institute; National Research Foundation; European Commission","keywords":"Biology; Genome-wide association study; Body mass index; Offspring; Genetics; Framingham Heart Study; Obesity; Heritability; Pedigree chart; Minor allele frequency; Waist; Internal medicine; Endocrinology; Single-nucleotide polymorphism; Framingham Risk Score; Genotype; Gene; Medicine; Disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001778696,0.0004228473,0.0006610063,0.0006745494,0.0003525875,0.0006822024,0.000337621,0.0003397001,0.001110202],"category_scores_gemma":[0.003395668,0.0003644908,0.0008902531,0.001040029,0.0003283823,0.0002003586,0.0003895561,0.0004821164,0.0001428843],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001444225,"about_ca_system_score_gemma":0.0001864982,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003248252,"about_ca_topic_score_gemma":0.004317405,"domain_scores_codex":[0.9990296,0.0003487564,0.00009238207,0.0003487163,0.0001256512,0.00005483133],"domain_scores_gemma":[0.9982925,0.0008252588,0.0004524776,0.0002465128,0.00009335738,0.00008992958],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001541869,0.00003616139,0.9834403,0.0001588498,0.003047757,0.0005653414,0.0002070512,0.0001358263,0.002665222,0.00007409645,0.0001512689,0.007976241],"study_design_scores_gemma":[0.00004507697,0.0001312251,0.9975153,0.00002500847,0.001250092,0.000255109,0.00005954992,0.0001478264,0.0002282666,0.00006288759,0.0002764707,0.000003132435],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9938344,0.004789269,0.0005824156,0.00007432381,0.00002908636,0.000007594508,0.0003253822,0.00001502335,0.0003425438],"genre_scores_gemma":[0.9978315,0.001127967,0.0004108268,0.00005620536,0.00003221894,0.000008186466,0.0003392547,0.000007861449,0.000185978],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003248252,"threshold_uncertainty_score":0.009406745,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02068337992710607,"score_gpt":0.2581751737613202,"score_spread":0.2374917938342141,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}