{"id":"W1949373242","doi":"10.1038/onc.2015.180","title":"Decoy receptors block TRAIL sensitivity at a supracellular level: the role of stromal cells in controlling tumour TRAIL sensitivity","year":2015,"lang":"en","type":"article","venue":"Oncogene","topic":"Cell death mechanisms and regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":62,"is_retracted":false,"has_abstract":false,"ca_institutions":"Institute for Research in Immunology and Cancer","funders":"","keywords":"Stromal cell; Decoy; Receptor; Biology; Apoptosis; Cytokine; Programmed cell death; Extracellular matrix; Cell biology; Cancer research; Tumor necrosis factor alpha; Cytotoxic T cell; Cell; Immunology; In vitro; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001157703,0.0001949795,0.0002774257,0.00004402812,0.00006902923,0.00001479191,0.00009010651,0.0002104116,0.000006680821],"category_scores_gemma":[0.00006032363,0.0001582123,0.0001438849,0.0001087916,0.00006521116,0.000006515839,0.0001058903,0.0001057737,0.000006750781],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005700162,"about_ca_system_score_gemma":0.0001247257,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001606984,"about_ca_topic_score_gemma":0.001310487,"domain_scores_codex":[0.9984826,0.0003558228,0.000288005,0.0003565613,0.000226812,0.0002902108],"domain_scores_gemma":[0.9992405,0.00005060037,0.0001587219,0.00031427,0.000118453,0.0001175117],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001621661,0.00009430269,0.0003390413,0.000006020147,0.00003384541,0.00002074004,0.0001792599,0.003569501,0.9912206,0.00003924392,0.00008572996,0.004249564],"study_design_scores_gemma":[0.001146736,0.000187684,0.0005262364,0.00001109804,0.00002969588,0.00006154527,0.0002889846,0.007286165,0.9821001,0.00007073065,0.00810265,0.0001883807],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9956224,0.0008701143,0.002581857,0.0001238486,0.0001989197,0.0002603254,0.00005184261,0.0000101973,0.0002805144],"genre_scores_gemma":[0.9980012,0.00008108263,0.001095712,0.00003988301,0.0001832885,0.000006407787,0.00006940329,0.00002495128,0.000498033],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009120492,"threshold_uncertainty_score":0.6451712,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01798666464879451,"score_gpt":0.2284214644704333,"score_spread":0.2104347998216388,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}