{"id":"W1949720728","doi":"10.1186/gb-2001-3-1-research0002","title":"Functional and phylogenetic analysis of the ubiquitylation system in Caenorhabditis elegans: ubiquitin-conjugating enzymes, ubiquitin-activating enzymes, and ubiquitin-like proteins","year":2001,"lang":"en","type":"article","venue":"Genome biology","topic":"Ubiquitin and proteasome pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":183,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research","keywords":"Biology; Ubiquitin; RNA interference; NEDD8; Caenorhabditis elegans; Ubiquitin ligase; Ubiquitin-conjugating enzyme; Ubiquitin-Protein Ligases; Genetics; Yeast; Biochemistry; Cell biology; Gene; RNA","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001243951,0.0004221953,0.0001808414,0.001599971,0.0005718196,0.0001834294,0.0002838682,0.0002834561,0.0005669881],"category_scores_gemma":[0.0001240879,0.0001327936,0.0002457469,0.0005549219,0.0001752287,0.00014578,0.0001603676,0.0002641575,0.000308491],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004898377,"about_ca_system_score_gemma":0.0003105522,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.005361284,"about_ca_topic_score_gemma":0.005181411,"domain_scores_codex":[0.9999077,0.00000471357,0.00001084056,0.00003402718,0.00002601876,0.00001666589],"domain_scores_gemma":[0.9998106,0.00001931044,0.00005077676,0.0000115645,0.00005223424,0.00005554518],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001783087,0.00005526724,0.009786122,0.0001121882,0.00001919599,0.000181634,0.00005073217,0.0001977569,0.9828728,0.0001451043,0.0001070016,0.006293787],"study_design_scores_gemma":[0.00003441791,0.0004868508,0.7815673,0.00008838597,0.0002185499,0.002491448,0.0002143033,0.003341489,0.1993246,0.0002399493,0.01194188,0.00005087884],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9916092,0.002245149,0.001522408,0.00004395071,0.00001123581,0.00004681434,0.00204582,0.00005381935,0.002421661],"genre_scores_gemma":[0.9851119,0.001129701,0.006478323,0.00007254184,0.000009595566,0.00007188971,0.005154159,0.00002137205,0.001950477],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005361284,"threshold_uncertainty_score":0.01066017,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.014008960719166,"score_gpt":0.2257043594510417,"score_spread":0.2116953987318757,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}