{"id":"W1950676599","doi":"10.1002/eji.201242935","title":"Complement opsonization of <scp>HIV</scp>‐1 results in a different intracellular processing pattern and enhanced <scp>MHC</scp> class I presentation by dendritic cells","year":2013,"lang":"en","type":"article","venue":"European Journal of Immunology","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canadian Science Centre for Human and Animal Health; University of Manitoba","funders":"National Institute of Allergy and Infectious Diseases; National Cancer Institute; National Institutes of Health; Vetenskapsrådet; Svenska Läkaresällskapet; Linköpings Universitet; Styrelsen för Internationellt Utvecklingssamarbete","keywords":"Antibody opsonization; Antigen processing; Antigen presentation; Biology; Cross-presentation; MHC class I; Complement receptor; Cell biology; Antigen; Endocytic cycle; Immunology; Opsonin; Complement system; Major histocompatibility complex; Receptor; T cell; Immune system; Endocytosis; Phagocytosis; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000511034,0.0002324956,0.0004518077,0.0002854833,0.0001076953,0.00004564903,0.0002920923,0.00008930913,0.00004204941],"category_scores_gemma":[0.0003485834,0.0001854229,0.0000668604,0.0001451872,0.0002775436,0.0002029754,0.000140134,0.0004893077,0.0001881951],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007695516,"about_ca_system_score_gemma":0.00005434819,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003738528,"about_ca_topic_score_gemma":0.0000113615,"domain_scores_codex":[0.9966717,0.001468439,0.001007519,0.0002633932,0.0001024868,0.0004864713],"domain_scores_gemma":[0.9982801,0.0004720641,0.0007085948,0.0001909177,0.0002906272,0.00005769162],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005173678,0.0004842961,0.002905649,0.00005408523,0.0002552219,0.00006148761,0.002988041,0.00001932578,0.962768,0.000006646348,0.004702719,0.02570275],"study_design_scores_gemma":[0.01003519,0.002222722,0.1109405,0.000329422,0.00007159996,0.0002019827,0.00389842,0.00006611332,0.8659119,0.00003686208,0.006207942,0.00007730335],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9870669,0.006716156,0.004790269,0.0002352918,0.0002028283,0.0004004504,0.00006014237,0.00001221886,0.000515757],"genre_scores_gemma":[0.9979919,0.0008472726,0.0001300044,0.00003285644,0.00003044857,0.000009978026,0.0001980196,0.00002814893,0.0007313229],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1080349,"threshold_uncertainty_score":0.7561327,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01139314361136427,"score_gpt":0.2337712867740194,"score_spread":0.2223781431626551,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}