{"id":"W1950676599","doi":"10.1002/eji.201242935","title":"Complement opsonization of <scp>HIV</scp>‐1 results in a different intracellular processing pattern and enhanced <scp>MHC</scp> class I presentation by dendritic cells","year":2013,"lang":"en","type":"article","venue":"European Journal of Immunology","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canadian Science Centre for Human and Animal Health; University of Manitoba","funders":"National Institute of Allergy and Infectious Diseases; National Cancer Institute; National Institutes of Health; Vetenskapsrådet; Svenska Läkaresällskapet; Linköpings Universitet; Styrelsen för Internationellt Utvecklingssamarbete","keywords":"Antibody opsonization; Antigen processing; Antigen presentation; Biology; Cross-presentation; MHC class I; Complement receptor; Cell biology; Antigen; Endocytic cycle; Immunology; Opsonin; Complement system; Major histocompatibility complex; Receptor; T cell; Immune system; Endocytosis; Phagocytosis; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007947245,0.0003061981,0.000208816,0.000165514,0.0001192616,0.0002818446,0.0001445922,0.0002853982,0.001458015],"category_scores_gemma":[0.0001198774,0.00009877327,0.0002743131,0.0001604718,0.0001948092,0.0001501187,0.0001217319,0.0005000731,0.0002404096],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000551205,"about_ca_system_score_gemma":0.0002787189,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002740521,"about_ca_topic_score_gemma":0.001862084,"domain_scores_codex":[0.9998366,0.00001443383,0.00001406452,0.0000279213,0.00004160532,0.00006537362],"domain_scores_gemma":[0.999916,0.00002104454,0.00001501228,0.00001229914,0.00001421857,0.00002154353],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009895225,0.00001375222,0.0001127977,0.00001531093,0.000002954774,0.00004418376,0.000005919298,0.0000257755,0.9992506,0.00005247783,0.00001724877,0.0003599767],"study_design_scores_gemma":[0.000007855718,0.0001479166,0.004617815,0.000002903707,0.000009237506,0.0002156122,0.00001272063,0.0003477833,0.9940362,0.00002793212,0.0005706268,0.000003489676],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9976295,0.0005723669,0.0006651709,0.00003638458,0.0000155085,0.0000177237,0.0002396882,0.00001753828,0.0008060283],"genre_scores_gemma":[0.9963134,0.000341725,0.0009586391,0.00005421347,0.000009288817,0.00002521646,0.0006501637,0.00001220789,0.001635066],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002740521,"threshold_uncertainty_score":0.005449116,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01139314361136427,"score_gpt":0.2337712867740194,"score_spread":0.2223781431626551,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}