{"id":"W1950994326","doi":"10.1002/9780470015902.a0006019.pub2","title":"Tay–Sachs Disease","year":2010,"lang":"en","type":"other","venue":"Encyclopedia of Life Sciences","topic":"Lysosomal Storage Disorders Research","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Hospital for Sick Children","funders":"","keywords":"Sandhoff disease; Gangliosidosis; Disease; Tay-Sachs disease; Computational biology; Biology; Neuroscience; Medicine; Bioinformatics; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001119423,0.0005991725,0.0003274838,0.001221407,0.0004711227,0.0006178218,0.000164414,0.0005171982,0.0265097],"category_scores_gemma":[0.0003654998,0.00005613596,0.0002127794,0.001097356,0.000337385,0.0003845673,0.0005026545,0.0003752599,0.007388697],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002991939,"about_ca_system_score_gemma":0.0003575711,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001112718,"about_ca_topic_score_gemma":0.00106462,"domain_scores_codex":[0.9998962,0.00001309107,0.00001254829,0.00002311333,0.00003376788,0.00002131323],"domain_scores_gemma":[0.999902,0.0000216737,0.00002154247,0.000008682928,0.00001686509,0.00002920756],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000532913,0.0002060176,0.03200006,0.001761044,0.0001624255,0.0577922,0.0006014533,0.0005097346,0.02232264,0.02821026,0.1737367,0.6821645],"study_design_scores_gemma":[0.00008776063,0.0001697722,0.03302722,0.0005310848,0.0001193267,0.2809324,0.0002263324,0.0005079816,0.008127581,0.007147144,0.6690896,0.00003370106],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"other","genre_gemma":"other","genre_scores_codex":[0.2097095,0.1763934,0.008486961,0.00565962,0.002213911,0.0002193266,0.00487137,0.001208468,0.5912375],"genre_scores_gemma":[0.6414215,0.07712457,0.005228655,0.002147632,0.001489899,0.00009172948,0.004738947,0.00008411398,0.267673],"genre_candidate":"other","genre_consensus":"other","teacher_disagreement_score":0.0265097,"threshold_uncertainty_score":0.08868378,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02055983085213598,"score_gpt":0.3143488370301014,"score_spread":0.2937890061779654,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}