{"id":"W1950994326","doi":"10.1002/9780470015902.a0006019.pub2","title":"Tay–Sachs Disease","year":2010,"lang":"en","type":"other","venue":"Encyclopedia of Life Sciences","topic":"Lysosomal Storage Disorders Research","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Hospital for Sick Children","funders":"","keywords":"Sandhoff disease; Gangliosidosis; Disease; Tay-Sachs disease; Computational biology; Biology; Neuroscience; Medicine; Bioinformatics; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0003521653,0.0002391268,0.0004823116,0.0005150777,0.00007874091,0.00001551134,0.0005724673,0.0002330724,0.01305546],"category_scores_gemma":[0.001389308,0.0001788039,0.0001516113,0.000601442,0.001280608,0.00006206687,0.0001395208,0.0004217241,0.0003746418],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001591051,"about_ca_system_score_gemma":0.001543607,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005634293,"about_ca_topic_score_gemma":0.000182934,"domain_scores_codex":[0.9974202,0.00004722925,0.0002815377,0.0005224885,0.001314823,0.0004137085],"domain_scores_gemma":[0.9985462,0.00008052962,0.0002053765,0.0004784034,0.00006707782,0.000622445],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00005158412,0.000243108,0.05839526,0.0004302618,0.00004699018,0.00005938672,0.00009193937,5.597737e-7,0.00005549677,0.0002999086,0.9333861,0.006939337],"study_design_scores_gemma":[0.0004122745,0.0001453354,0.00698382,0.0001984981,0.00005311899,0.000002796774,0.00007666732,0.00001717474,0.000009837994,0.0001312899,0.9917585,0.0002106945],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"other","genre_gemma":"other","genre_scores_codex":[0.003105424,0.007651984,0.00001466729,0.00109003,0.0007422413,0.0005438252,0.00005258447,0.0001094116,0.9866898],"genre_scores_gemma":[0.005378385,0.004579197,0.001799053,0.0002945449,0.001196133,0.0000375863,0.00002561725,0.0001945904,0.9864949],"genre_candidate":"other","genre_consensus":"other","teacher_disagreement_score":0.05837233,"threshold_uncertainty_score":0.9878467,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02055983085213598,"score_gpt":0.3143488370301014,"score_spread":0.2937890061779654,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}