{"id":"W1951033865","doi":"10.1242/dev.127.3.533","title":"Formation of corneal endothelium is essential for anterior segment development – a transgenic mouse model of anterior segment dysgenesis","year":2000,"lang":"en","type":"article","venue":"Development","topic":"Corneal Surgery and Treatments","field":"Medicine","cited_by":110,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Cegep de Saint Hyacinthe","funders":"National Eye Institute","keywords":"Biology; Corneal endothelium; Cornea; IRIS (biosensor); Eye development; Ciliary body; Anatomy; Stroma; Cell biology; Corneal epithelium; Dysgenesis; Genetically modified mouse; Lens (geology); Epithelium; Transgene; Immunology; Neuroscience; Genetics; Transcription factor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002730945,0.0006056097,0.0003527152,0.0008841184,0.0004403669,0.0004993994,0.0004333456,0.000885407,0.003146302],"category_scores_gemma":[0.0002142701,0.0003951638,0.0003553065,0.000334241,0.0008400493,0.0004535727,0.0003127786,0.001236975,0.000825621],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004202356,"about_ca_system_score_gemma":0.0005233909,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007257907,"about_ca_topic_score_gemma":0.001072058,"domain_scores_codex":[0.9996598,0.00005656507,0.00004614712,0.00007522647,0.0001084362,0.00005389314],"domain_scores_gemma":[0.999569,0.00005964283,0.0001596317,0.00006049431,0.0000302495,0.0001209698],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002643747,0.0001748021,0.0002740099,0.00003320686,0.000007932711,0.0003678021,0.00003488463,0.0001032475,0.9961372,0.0009613716,0.000142786,0.001498322],"study_design_scores_gemma":[0.0003556332,0.001605598,0.005118858,0.00004205942,0.00008464864,0.003105014,0.00007638583,0.003196046,0.9696532,0.0006411846,0.01610083,0.00002056713],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9858162,0.001252255,0.006603803,0.0005839904,0.0001221217,0.0001338345,0.0009154328,0.0004281471,0.004144247],"genre_scores_gemma":[0.9704099,0.001694526,0.01041774,0.000172375,0.00005514083,0.0002631038,0.001383809,0.0001471198,0.01545633],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003146302,"threshold_uncertainty_score":0.01052541,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02470566883909816,"score_gpt":0.2558632412795608,"score_spread":0.2311575724404627,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}