{"id":"W1951033865","doi":"10.1242/dev.127.3.533","title":"Formation of corneal endothelium is essential for anterior segment development – a transgenic mouse model of anterior segment dysgenesis","year":2000,"lang":"en","type":"article","venue":"Development","topic":"Corneal Surgery and Treatments","field":"Medicine","cited_by":110,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Cegep de Saint Hyacinthe","funders":"National Eye Institute","keywords":"Biology; Corneal endothelium; Cornea; IRIS (biosensor); Eye development; Ciliary body; Anatomy; Stroma; Cell biology; Corneal epithelium; Dysgenesis; Genetically modified mouse; Lens (geology); Epithelium; Transgene; Immunology; Neuroscience; Genetics; Transcription factor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002613265,0.0003306951,0.0006922643,0.0001576415,0.0001197285,0.00001148304,0.0001185939,0.000102109,0.0004645067],"category_scores_gemma":[0.000005751422,0.0002940162,0.0002334292,0.0001438341,0.00004758922,0.0001232087,0.00003431476,0.00005774725,0.00002691432],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002972647,"about_ca_system_score_gemma":0.0005529521,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001511792,"about_ca_topic_score_gemma":0.00001897738,"domain_scores_codex":[0.9974616,0.00002506941,0.001230478,0.0003722993,0.0004920276,0.0004184875],"domain_scores_gemma":[0.9991051,0.00003142291,0.0002647471,0.0002676467,0.0001618234,0.0001692446],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.005045116,0.002608664,0.004721949,0.001866853,0.001087064,0.00001153148,0.01661354,0.0002213117,0.419866,0.000008420202,0.0002037673,0.5477458],"study_design_scores_gemma":[0.003910305,0.0002447398,0.007823294,0.0004115433,0.000159981,0.00001395383,0.000110904,0.001701577,0.9838643,0.000006435459,0.001484919,0.0002680378],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9830801,0.0001442226,0.01489017,0.00009934499,0.00008550403,0.001373595,0.0001396522,0.00004179799,0.0001455519],"genre_scores_gemma":[0.9660662,0.0002576505,0.03040417,0.0001693584,0.00002090292,0.0003703415,0.0001448174,0.00003815581,0.002528439],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5639983,"threshold_uncertainty_score":0.9999512,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02470566883909816,"score_gpt":0.2558632412795608,"score_spread":0.2311575724404627,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}