{"id":"W1952021403","doi":"10.1200/jco.2006.24.18_suppl.10106","title":"Regulation of IKKe expression by androgen receptor and NF-kB transcriptional factor in prostate cancer","year":2006,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"NF-κB Signaling Pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre Hospitalier de l’Université de Montréal","funders":"","keywords":"LNCaP; DU145; Androgen receptor; Tumor necrosis factor alpha; Transcription factor; Biology; Androgen; Cancer research; Signal transduction; Kinase; Transfection; Cell culture; Prostate cancer; Molecular biology; Endocrinology; Internal medicine; Cell biology; Medicine; Cancer; Gene; Hormone; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007888026,0.00008775665,0.0004165753,0.00004550659,0.00001685649,0.000004179767,0.00008838464,0.0002756928,0.00005724232],"category_scores_gemma":[0.000214354,0.00007043354,0.0001254305,0.0000449508,0.0001207759,0.000009595646,0.00002135938,0.0002134981,5.1022e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002530987,"about_ca_system_score_gemma":0.0003269512,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003022635,"about_ca_topic_score_gemma":0.00006276897,"domain_scores_codex":[0.998152,0.000238736,0.001170602,0.0001599639,0.0001577073,0.0001210269],"domain_scores_gemma":[0.9987441,0.0001155127,0.0008183616,0.0000773725,0.0001668835,0.00007778533],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001043474,0.0002750125,0.06476484,0.000012529,0.00002396593,0.000003341387,0.00002693971,0.00008998476,0.9218311,0.00001571179,0.004269004,0.007644077],"study_design_scores_gemma":[0.005219569,0.003343836,0.1829976,0.0001016909,0.00003465295,0.00002793976,0.00003057382,0.00003961711,0.6908861,0.0005146707,0.116646,0.0001576476],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9963964,0.002269171,0.0002067436,0.0005514159,0.0003185808,0.00009362978,0.00005728794,0.000001491317,0.0001052927],"genre_scores_gemma":[0.9970704,0.0007012335,0.001454743,0.0001169697,0.0004064605,0.000003567433,0.00002733219,0.00001004079,0.0002092051],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.230945,"threshold_uncertainty_score":0.2872196,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04569172435458461,"score_gpt":0.3793882390537828,"score_spread":0.3336965146991981,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}