{"id":"W1952799215","doi":"10.1002/9780470571224.pse188","title":"Preclinical Safety Evaluation of Immunotoxins","year":2010,"lang":"en","type":"other","venue":"Pharmaceutical Sciences Encyclopedia","topic":"Toxin Mechanisms and Immunotoxins","field":"Immunology and Microbiology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Viventia Bio (Canada)","funders":"","keywords":"Immunotoxin; Pseudomonas exotoxin; In vivo; In vitro; Recombinant DNA; Antibody; Exotoxin; Cancer research; Computational biology; Medicine; Chemistry; Toxin; Immunology; Biology; Monoclonal antibody; Microbiology; Biotechnology; Gene; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001888678,0.0005792583,0.0004343659,0.0005023753,0.0002920776,0.0006116509,0.0004537494,0.0006739374,0.005631288],"category_scores_gemma":[0.001091392,0.0001390679,0.0004155296,0.0002636412,0.0003454208,0.0003557787,0.0002476082,0.0008784977,0.0009863169],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005707001,"about_ca_system_score_gemma":0.0008631603,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004788707,"about_ca_topic_score_gemma":0.0006579571,"domain_scores_codex":[0.9991893,0.0002946113,0.00005007014,0.00008923346,0.0002871095,0.00008980434],"domain_scores_gemma":[0.999301,0.0001373351,0.0001447936,0.00008955479,0.0002392379,0.0000882043],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.01169161,0.008497966,0.002593701,0.001371617,0.0001970613,0.000462109,0.0002249919,0.003555417,0.767902,0.003751102,0.005952695,0.1937997],"study_design_scores_gemma":[0.001635738,0.1321335,0.006285671,0.0002815393,0.0002874856,0.001262217,0.0001197563,0.002706129,0.7738177,0.0009169617,0.08052292,0.00003047772],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"other","genre_scores_codex":[0.9120255,0.01346175,0.02788425,0.001095625,0.0007904676,0.004672768,0.003315091,0.0004231958,0.0363313],"genre_scores_gemma":[0.9624423,0.007410086,0.006723679,0.0004130482,0.0001844902,0.001265707,0.002525477,0.00004611748,0.01898905],"genre_candidate":"other","genre_consensus":null,"teacher_disagreement_score":0.005631288,"threshold_uncertainty_score":0.01883858,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06463846988649058,"score_gpt":0.3847948038219513,"score_spread":0.3201563339354607,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}