{"id":"W1953028498","doi":"10.1002/pds.3859","title":"Benefit–Risk Assessment, Communication, and Evaluation (BRACE) throughout the life cycle of therapeutic products: overall perspective and role of the pharmacoepidemiologist","year":2015,"lang":"en","type":"review","venue":"Pharmacoepidemiology and Drug Safety","topic":"Health Systems, Economic Evaluations, Quality of Life","field":"Economics, Econometrics and Finance","cited_by":26,"is_retracted":false,"has_abstract":true,"ca_institutions":"Purdue Pharma (Canada)","funders":"International Society for Pharmacoepidemiology","keywords":"Medicine; Risk analysis (engineering); Risk assessment; Process (computing); Brace; Product (mathematics); Population; Engineering; Computer science; Environmental health; Computer security","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.1503997,0.00182726,0.002503256,0.008692661,0.002942141,0.01946049,0.003896342,0.005938245,0.002614884],"category_scores_gemma":[0.1489382,0.001162984,0.003041416,0.004599528,0.01114506,0.01276024,0.00937773,0.01076777,0.0006346951],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.01389965,"about_ca_system_score_gemma":0.03708334,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003689444,"about_ca_topic_score_gemma":0.005008545,"domain_scores_codex":[0.8177522,0.1443027,0.008913303,0.003320566,0.02315228,0.002558926],"domain_scores_gemma":[0.7879431,0.1681824,0.01663534,0.006745453,0.01802121,0.002472395],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0004923973,0.0002897649,0.005074523,0.01072417,0.0009055874,0.0006836136,0.004893459,0.01328218,0.0008368389,0.3127438,0.0167592,0.6333145],"study_design_scores_gemma":[0.0003189686,0.001553937,0.006263542,0.04415425,0.001660393,0.003207002,0.01174965,0.01939769,0.005039027,0.582616,0.3235105,0.0005289376],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"commentary","genre_gemma":"review","genre_scores_codex":[0.02033349,0.2626154,0.2923488,0.3471982,0.001885843,0.002418202,0.0003140427,0.0003887276,0.07249736],"genre_scores_gemma":[0.4301057,0.119371,0.4087364,0.03361826,0.001831978,0.002160801,0.0002409746,0.0001650327,0.003769721],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.1503997,"threshold_uncertainty_score":0.7953993,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.3636447492913812,"score_gpt":0.5444831307921081,"score_spread":0.1808383815007268,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}