{"id":"W1954303790","doi":"10.1016/j.neuroscience.2015.08.044","title":"The Val66Met brain-derived neurotrophic factor gene variant interacts with early pain exposure to predict cortisol dysregulation in 7-year-old children born very preterm: Implications for cognition","year":2015,"lang":"en","type":"review","venue":"Neuroscience","topic":"Pediatric Pain Management Techniques","field":"Medicine","cited_by":49,"is_retracted":false,"has_abstract":false,"ca_institutions":"Child and Family Research Institute; University of British Columbia","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; Canadian Institutes of Health Research","keywords":"Neurotrophic factors; Brain-derived neurotrophic factor; Psychology; Internal medicine; Cognition; Endocrinology; Effects of sleep deprivation on cognitive performance; Medicine; Neuroscience; Receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001054771,0.0004161234,0.0007421558,0.0004391483,0.0001889674,0.0001853427,0.0006353554,0.0001599334,0.000001303136],"category_scores_gemma":[0.002418161,0.0002952515,0.0001530824,0.001116074,0.0001469987,0.0002552052,0.0001727024,0.0004012741,0.000004310854],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001774434,"about_ca_system_score_gemma":0.0004358301,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001546606,"about_ca_topic_score_gemma":0.000007072473,"domain_scores_codex":[0.9968349,0.0005371626,0.0006783477,0.0009321043,0.0005079008,0.0005095563],"domain_scores_gemma":[0.9974778,0.0006699784,0.0005010131,0.0009040495,0.0002069718,0.000240207],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.0006356812,0.0006222992,0.02933764,0.004081939,0.0001241693,0.00010346,0.0002800651,0.00004178325,0.003824824,0.0001425088,0.009553416,0.9512522],"study_design_scores_gemma":[0.00146654,0.006445646,0.926978,0.004509702,0.0009113167,0.0002032273,0.000004040854,0.0003537908,0.00002268202,0.000175621,0.05812167,0.00080775],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.1895694,0.4489485,0.2253217,0.007466778,0.00235943,0.1194473,0.003319209,0.002983337,0.000584437],"genre_scores_gemma":[0.1669137,0.8160638,0.003470479,0.004543695,0.0007313604,0.006884788,0.0006685915,0.0002776779,0.0004458759],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9504445,"threshold_uncertainty_score":0.9999499,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04648781372121474,"score_gpt":0.3207914139819809,"score_spread":0.2743036002607661,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}