{"id":"W1955371253","doi":"10.1038/onc.2015.244","title":"TRM6/61 connects PKCα with translational control through tRNAiMet stabilization: impact on tumorigenesis","year":2015,"lang":"en","type":"article","venue":"Oncogene","topic":"RNA modifications and cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":88,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Institute of Cancer Research; Institut Gustave-Roussy; Institut National Du Cancer; Swedish Cancer Foundation","keywords":"Biology; Carcinogenesis; Protein kinase C; Translation (biology); Translational regulation; Protein biosynthesis; Messenger RNA; Cell biology; Molecular biology; Signal transduction; Cancer research; Biochemistry; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001263905,0.0001654362,0.0001559853,0.00002460446,0.00008917759,0.00003319975,0.000117542,0.00008425789,0.0001845164],"category_scores_gemma":[0.00002077963,0.0001219108,0.00007908249,0.0001285195,0.00007246065,0.000008036061,0.000006797584,0.00004225428,0.00003726079],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003902228,"about_ca_system_score_gemma":0.0004358931,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003650272,"about_ca_topic_score_gemma":0.00003428542,"domain_scores_codex":[0.9990763,0.00006157216,0.0001612698,0.0003045057,0.0002117591,0.000184608],"domain_scores_gemma":[0.9992729,0.00001506374,0.00007572881,0.0003206028,0.0001974832,0.0001181697],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.008198528,0.0013058,0.0221667,0.00004309611,0.001107744,0.00003221551,0.0008864159,0.09199107,0.8230169,0.003637084,0.02419035,0.0234241],"study_design_scores_gemma":[0.01746401,0.008366303,0.01470338,0.00005752325,0.000303444,0.0001363955,0.0003815655,0.00211613,0.5262388,0.0008890941,0.4278121,0.001531249],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9485428,0.001638845,0.04144685,0.0005826289,0.0001065402,0.0003430027,0.0001962785,0.00002272781,0.007120261],"genre_scores_gemma":[0.9975783,0.00005092152,0.0005961548,0.0003218326,0.0003223015,0.00006170516,0.0002735234,0.00002779767,0.0007675024],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4036218,"threshold_uncertainty_score":0.4971377,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02490319926882621,"score_gpt":0.2947661761225308,"score_spread":0.2698629768537045,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}