{"id":"W1955371253","doi":"10.1038/onc.2015.244","title":"TRM6/61 connects PKCα with translational control through tRNAiMet stabilization: impact on tumorigenesis","year":2015,"lang":"en","type":"article","venue":"Oncogene","topic":"RNA modifications and cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":88,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Institute of Cancer Research; Institut Gustave-Roussy; Institut National Du Cancer; Swedish Cancer Foundation","keywords":"Biology; Carcinogenesis; Protein kinase C; Translation (biology); Translational regulation; Protein biosynthesis; Messenger RNA; Cell biology; Molecular biology; Signal transduction; Cancer research; Biochemistry; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004193544,0.0004133524,0.0003190962,0.0002512601,0.0004619514,0.0006332947,0.0005265541,0.0007895686,0.005798792],"category_scores_gemma":[0.0004622106,0.0002105277,0.0004649307,0.0002282249,0.0005334464,0.0005556065,0.0006351265,0.001134715,0.002285511],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004529881,"about_ca_system_score_gemma":0.000318735,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003416202,"about_ca_topic_score_gemma":0.0003158847,"domain_scores_codex":[0.9997126,0.00003768515,0.00003223929,0.00007640546,0.00006561841,0.00007531868],"domain_scores_gemma":[0.9996941,0.00002552709,0.000107523,0.00006834701,0.00002667573,0.00007786114],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0009517777,0.0000734673,0.001342346,0.0000683446,0.00001890523,0.0002848493,0.00002386151,0.0002534587,0.9891852,0.001403841,0.0002562933,0.006137751],"study_design_scores_gemma":[0.00006396697,0.0003258832,0.006941504,0.00001750055,0.00002797465,0.0008177831,0.00006048307,0.001303967,0.9830095,0.0007645991,0.006655048,0.00001165225],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.988306,0.002821879,0.004104344,0.0009399678,0.0002164715,0.00002088247,0.0003278453,0.0002273505,0.003035276],"genre_scores_gemma":[0.9953895,0.0005764306,0.0009327313,0.0001250798,0.00002717724,0.000007881325,0.0002635026,0.00003653705,0.00264127],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005798792,"threshold_uncertainty_score":0.01939887,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02490319926882621,"score_gpt":0.2947661761225308,"score_spread":0.2698629768537045,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}