{"id":"W1958271805","doi":"10.1007/s11307-015-0877-x","title":"Evaluation of PET Imaging Performance of the TSPO Radioligand [18F]DPA-714 in Mouse and Rat Models of Cancer and Inflammation","year":2015,"lang":"en","type":"article","venue":"Molecular Imaging and Biology","topic":"Protein Kinase Regulation and GTPase Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; University Health Network","funders":"","keywords":"Radioligand; Pet imaging; Medicine; Inflammation; Nuclear medicine; Positron emission tomography; Internal medicine; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008835496,0.001087359,0.00063605,0.0008439477,0.0002384621,0.0004160076,0.0004809634,0.0008924077,0.001445491],"category_scores_gemma":[0.0002925341,0.0004026299,0.0005027609,0.0004056155,0.0005646045,0.0006780124,0.000189191,0.0009708321,0.0004718061],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005625624,"about_ca_system_score_gemma":0.0003740341,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001538978,"about_ca_topic_score_gemma":0.001369258,"domain_scores_codex":[0.9996705,0.00008324113,0.00001859603,0.00006795648,0.00006043678,0.00009935362],"domain_scores_gemma":[0.999688,0.00006050688,0.00008345999,0.00003879593,0.00006257199,0.00006671059],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002017864,0.0002664369,0.0006377766,0.0001130459,0.0000377106,0.0001020931,0.00003732327,0.0002894176,0.9935574,0.0001395809,0.00009172888,0.002709754],"study_design_scores_gemma":[0.0001100635,0.008473551,0.004805499,0.00001461393,0.0002247486,0.0007021073,0.00007450618,0.002022207,0.9814177,0.00007342616,0.002057013,0.00002453125],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9824875,0.005754254,0.009192635,0.0002067232,0.00005888527,0.00008994975,0.0004953504,0.0002304396,0.001484281],"genre_scores_gemma":[0.9692008,0.006255387,0.01653241,0.0001673993,0.00004478955,0.0003650701,0.001434042,0.0001233619,0.005876641],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001538978,"threshold_uncertainty_score":0.004835665,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02065091200449979,"score_gpt":0.2814423671019521,"score_spread":0.2607914550974523,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}