{"id":"W1960194941","doi":"10.4049/jimmunol.170.6.3323","title":"Redundancy of a Functional Melanocortin 1 Receptor in the Anti-inflammatory Actions of Melanocortin Peptides: Studies in the Recessive Yellow (e/e) Mouse Suggest an Important Role for Melanocortin 3 Receptor","year":2003,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"melanin and skin pigmentation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":84,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Vetenskapsrådet; Wellcome Trust; Université de Sherbrooke","keywords":"Melanocortin; Melanocortins; Melanocortin 3 receptor; Melanocortin receptor; Agonist; Melanocortin 4 receptor; Internal medicine; Endocrinology; Receptor; Melanocortin 1 receptor; Melanocyte-stimulating hormone; Biology; In vivo; Antagonist; Hormone; Phenotype; Biochemistry; Medicine; Gene; Genetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005049969,0.0007628571,0.0004832084,0.0006411548,0.0001905801,0.0005272829,0.0004088641,0.0007391375,0.002174062],"category_scores_gemma":[0.0002500036,0.0003625228,0.0005629325,0.0001664795,0.0006464987,0.0005354806,0.000447511,0.0008801574,0.0006119772],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002335111,"about_ca_system_score_gemma":0.0001707134,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002179578,"about_ca_topic_score_gemma":0.0003042578,"domain_scores_codex":[0.999595,0.00006797156,0.00005003971,0.0001162234,0.00009313285,0.00007758673],"domain_scores_gemma":[0.9992893,0.000125848,0.0002964918,0.00009252937,0.00004119246,0.0001546447],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001047326,0.000009881172,0.0001921616,0.00001702733,0.000003384295,0.0001080335,0.000007762644,0.00001567167,0.9991403,0.00006586741,0.000007392079,0.000327857],"study_design_scores_gemma":[0.00004758267,0.0006373215,0.01298342,0.00001905712,0.00006239284,0.002291868,0.00007302584,0.0007769124,0.9813722,0.0001649454,0.001557863,0.00001336883],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9920888,0.001872173,0.004577501,0.0001647565,0.00002111968,0.00002281582,0.0004134095,0.00009506327,0.0007442343],"genre_scores_gemma":[0.9900991,0.001116725,0.005121598,0.0001120818,0.00002063025,0.00004091628,0.000446131,0.00009248755,0.002950291],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002174062,"threshold_uncertainty_score":0.007272899,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03329943714073531,"score_gpt":0.3082033534961074,"score_spread":0.2749039163553721,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}