{"id":"W1960400112","doi":"10.1002/hep.28015","title":"Randomized, controlled trial of entecavir versus placebo in children with hepatitis B envelope antigen–positive chronic hepatitis B","year":2015,"lang":"en","type":"article","venue":"Hepatology","topic":"Hepatitis B Virus Studies","field":"Medicine","cited_by":106,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Gilead Sciences; Bristol-Myers Squibb","keywords":"Entecavir; Medicine; Seroconversion; HBeAg; Internal medicine; Gastroenterology; Placebo; Clinical endpoint; Hepatitis B; Hepatitis B virus; Randomized controlled trial; HBsAg; Immunology; Antibody; Lamivudine; Virus; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002767931,0.001629874,0.004027827,0.0003855163,0.0005656352,0.001186033,0.001104604,0.001995061,0.01057102],"category_scores_gemma":[0.003863173,0.0007125625,0.00160186,0.0003743815,0.001272251,0.001181448,0.0004509485,0.003499332,0.001062686],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005484311,"about_ca_system_score_gemma":0.001251313,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007598092,"about_ca_topic_score_gemma":0.001936429,"domain_scores_codex":[0.9985739,0.0009416006,0.0001161412,0.0001608545,0.00008892516,0.0001185611],"domain_scores_gemma":[0.998054,0.0007420953,0.0005111651,0.00009818048,0.0001302233,0.0004643283],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9862642,0.002773832,0.0002843585,0.0008560793,0.0006017667,0.00002209213,0.00003015397,0.00009619244,0.0005416747,0.00006879652,0.0004344522,0.008026517],"study_design_scores_gemma":[0.9782001,0.02055193,0.0004220318,0.00003441686,0.0001656335,0.00001442875,0.00001045142,0.0001112028,0.00008971622,0.00003947429,0.0003562344,0.000004406967],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.956331,0.01718161,0.001575783,0.002402284,0.003725062,0.01212849,0.002207553,0.0003098133,0.004138486],"genre_scores_gemma":[0.9689634,0.006579468,0.003506509,0.002742169,0.001528063,0.01143123,0.0011812,0.00004006488,0.004027865],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01057102,"threshold_uncertainty_score":0.03536361,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02031860478465628,"score_gpt":0.2834332777325973,"score_spread":0.263114672947941,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}