{"id":"W1960400112","doi":"10.1002/hep.28015","title":"Randomized, controlled trial of entecavir versus placebo in children with hepatitis B envelope antigen–positive chronic hepatitis B","year":2015,"lang":"en","type":"article","venue":"Hepatology","topic":"Hepatitis B Virus Studies","field":"Medicine","cited_by":106,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Gilead Sciences; Bristol-Myers Squibb","keywords":"Entecavir; Medicine; Seroconversion; HBeAg; Internal medicine; Gastroenterology; Placebo; Clinical endpoint; Hepatitis B; Hepatitis B virus; Randomized controlled trial; HBsAg; Immunology; Antibody; Lamivudine; Virus; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001092684,0.0004417347,0.003871187,0.0004214325,0.00006623191,0.0000084627,0.0001722883,0.0002761079,0.0001177727],"category_scores_gemma":[0.001785332,0.0003353728,0.0003303059,0.0003855628,0.0008177846,0.0001131168,0.0001160202,0.0003827291,0.00007866119],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004946818,"about_ca_system_score_gemma":0.001169247,"about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_topic_score_codex":0.03120625,"about_ca_topic_score_gemma":0.04485691,"domain_scores_codex":[0.9960817,0.0009745287,0.001199169,0.000551094,0.0005566697,0.0006368893],"domain_scores_gemma":[0.9974654,0.0009576009,0.0005065147,0.0004441793,0.0003938452,0.0002324431],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.5076132,0.0002061147,0.4898942,0.000013151,0.0009876391,0.0001125208,0.0003409965,0.000002866214,0.000006476551,0.0002911838,0.0001717797,0.0003598842],"study_design_scores_gemma":[0.9334221,0.003988017,0.06025956,0.0001428119,0.0005278537,0.0001543924,0.00001890089,0.0005262491,0.0004143061,0.00005701007,0.0001936662,0.0002951621],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.982533,0.002497792,0.0001803618,0.0005286245,0.0006937347,0.008595871,0.00004233027,0.0000762062,0.004852114],"genre_scores_gemma":[0.9929369,0.004583757,0.0005085219,0.0001599113,0.0002300878,0.001300641,0.00008237187,0.00004643401,0.0001513808],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4296346,"threshold_uncertainty_score":0.9999098,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02031860478465628,"score_gpt":0.2834332777325973,"score_spread":0.263114672947941,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}