{"id":"W1960494757","doi":"10.1002/9780470015902.a0024904","title":"Molecular Genetics of the <scp>IPEX</scp> Syndrome","year":2015,"lang":"en","type":"other","venue":"Encyclopedia of Life Sciences","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; McGill University Health Centre","funders":"","keywords":"FOXP3; Autoimmunity; Primary immunodeficiency; Immune dysregulation; Immunology; Immune system; Immunodeficiency; Medicine; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001248316,0.0009664816,0.0002878203,0.001413644,0.0004306154,0.0004868664,0.0003505776,0.001114511,0.005213825],"category_scores_gemma":[0.000468623,0.0001437033,0.0004197661,0.0006174793,0.000635408,0.0003066562,0.0004470995,0.000721231,0.0006797921],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003076498,"about_ca_system_score_gemma":0.0002412933,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009817207,"about_ca_topic_score_gemma":0.0005086598,"domain_scores_codex":[0.9997836,0.00003363257,0.00002025851,0.00005984367,0.00006539228,0.00003728457],"domain_scores_gemma":[0.9997607,0.00009163676,0.00006418017,0.00001078467,0.00002245507,0.00005027505],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"case_report","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003967179,0.0000971265,0.0444729,0.0004504645,0.0001912179,0.7312487,0.0003768976,0.001255216,0.1646434,0.008488726,0.006950479,0.04142809],"study_design_scores_gemma":[0.00008185244,0.0001267678,0.07155422,0.0002633615,0.0002091304,0.8572486,0.000225348,0.002440238,0.03865412,0.003026696,0.02612505,0.00004462948],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"other","genre_scores_codex":[0.9611636,0.006094091,0.009045969,0.002089067,0.0003308133,0.0001363873,0.001321925,0.0004287606,0.01938945],"genre_scores_gemma":[0.9918235,0.001693928,0.002870145,0.0003681235,0.0002160082,0.00002958981,0.0004802866,0.00004025361,0.002478161],"genre_candidate":"other","genre_consensus":null,"teacher_disagreement_score":0.005213825,"threshold_uncertainty_score":0.01744199,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01224623133730457,"score_gpt":0.2357388029709039,"score_spread":0.2234925716335993,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}