{"id":"W1960538084","doi":"10.1111/j.1468-3083.2011.04373.x","title":"Efficacy, safety and tolerability of topical terbinafine nail solution in patients with mild‐to‐moderate toenail onychomycosis: results from three randomized studies using double‐blind vehicle‐controlled and open‐label active‐controlled designs","year":2011,"lang":"en","type":"article","venue":"Journal of the European Academy of Dermatology and Venereology","topic":"Nail Diseases and Treatments","field":"Medicine","cited_by":72,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Novartis Pharma; Novartis","keywords":"Medicine; Tolerability; Double blind; Terbinafine; Open label; Dermatology; Nail (fastener); Randomized controlled trial; Nail disease; Adverse effect; Surgery; Pharmacology; Placebo; Antifungal","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.005286813,0.001110432,0.003372009,0.0004769903,0.0004272404,0.0008882597,0.0008550143,0.001561999,0.003059868],"category_scores_gemma":[0.003747117,0.0005904321,0.00257012,0.0005297326,0.001349783,0.001020909,0.0003543401,0.001362,0.0003627217],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007658971,"about_ca_system_score_gemma":0.0009954543,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005424949,"about_ca_topic_score_gemma":0.001283673,"domain_scores_codex":[0.9968252,0.001958921,0.0004231848,0.0002870113,0.0002917561,0.000213933],"domain_scores_gemma":[0.9961109,0.001811183,0.001095315,0.0002831381,0.0002670672,0.0004325141],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9232314,0.01778476,0.001938154,0.001694015,0.002473689,0.00005256932,0.0001440187,0.0003730972,0.01392801,0.00007102273,0.0001909549,0.03811828],"study_design_scores_gemma":[0.6277457,0.3600525,0.007450205,0.00005669976,0.001887639,0.00006412828,0.00004959544,0.0003086042,0.001922214,0.00007659166,0.0003542916,0.00003174308],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9924447,0.004797876,0.0006471329,0.0001261891,0.00008409099,0.001328322,0.0001921936,0.00003502971,0.0003445029],"genre_scores_gemma":[0.9958453,0.001592039,0.0008701453,0.0001552588,0.0001188955,0.0009669286,0.0001844423,0.000007544852,0.0002594963],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005286813,"threshold_uncertainty_score":0.02795964,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1166435695795924,"score_gpt":0.3358654533715691,"score_spread":0.2192218837919767,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}