{"id":"W1961152800","doi":"10.4049/jimmunol.176.8.4826","title":"In Vivo Recognition of Ovalbumin Expressed by Transgenic <i>Leishmania</i> Is Determined by Its Subcellular Localization","year":2006,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Research on Leishmaniasis Studies","field":"Medicine","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Medical Research Council; Imperial College London; University of Pennsylvania; Wellcome Trust; National Institute of Allergy and Infectious Diseases; McMaster University; National Institutes of Health; London School of Hygiene and Tropical Medicine","keywords":"Biology; Leishmania major; Amastigote; Cell biology; Ovalbumin; Transgene; In vivo; CD8; MHC class I; Immunogenicity; Epitope; Leishmania; Secretion; Immunology; Antigen; Parasite hosting; Biochemistry; Gene; Genetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007863296,0.0001456851,0.0004956424,0.0002099245,0.00005450849,0.000006631421,0.0002260089,0.0001273701,0.0002435369],"category_scores_gemma":[0.0001518446,0.0001040624,0.0001149041,0.0002900152,0.0002006272,0.0001720084,0.00003032465,0.0003430126,0.00001091361],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009338528,"about_ca_system_score_gemma":0.00006886709,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001820453,"about_ca_topic_score_gemma":0.00002808583,"domain_scores_codex":[0.9981093,0.0003530021,0.0008046254,0.000111803,0.0003430662,0.0002781417],"domain_scores_gemma":[0.9987256,0.0002154845,0.0004292775,0.0001991334,0.0003977685,0.00003276116],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001229362,0.000288705,0.0004713938,0.00005590543,0.0001352315,0.00002219083,0.0005041376,0.000007263426,0.9514341,0.000003393937,0.04505484,0.0007934525],"study_design_scores_gemma":[0.003461256,0.0009412999,0.0006839066,0.0001509042,0.0001260296,0.0001916243,0.0002755614,0.00009991325,0.9857489,0.0002621653,0.007968551,0.00008983618],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9825037,0.01200923,0.001322423,0.003429803,0.000100829,0.0002796032,0.00002962219,0.000006973622,0.000317863],"genre_scores_gemma":[0.9933711,0.005448429,0.0000616091,0.000311681,0.00006593797,0.000005843776,0.00001041701,0.00002339241,0.0007016427],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03708629,"threshold_uncertainty_score":0.4243541,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01830708022454413,"score_gpt":0.2627857927148814,"score_spread":0.2444787124903373,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}