{"id":"W1961152800","doi":"10.4049/jimmunol.176.8.4826","title":"In Vivo Recognition of Ovalbumin Expressed by Transgenic <i>Leishmania</i> Is Determined by Its Subcellular Localization","year":2006,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Research on Leishmaniasis Studies","field":"Medicine","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Medical Research Council; Imperial College London; University of Pennsylvania; Wellcome Trust; National Institute of Allergy and Infectious Diseases; McMaster University; National Institutes of Health; London School of Hygiene and Tropical Medicine","keywords":"Biology; Leishmania major; Amastigote; Cell biology; Ovalbumin; Transgene; In vivo; CD8; MHC class I; Immunogenicity; Epitope; Leishmania; Secretion; Immunology; Antigen; Parasite hosting; Biochemistry; Gene; Genetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002204747,0.000426832,0.0002206436,0.0002422737,0.0001416418,0.0005013456,0.0002299597,0.0004461099,0.001372408],"category_scores_gemma":[0.0001581619,0.0002148433,0.000240782,0.0001272789,0.0003307727,0.000278525,0.0001915569,0.001187762,0.0006293547],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004597348,"about_ca_system_score_gemma":0.0001918591,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005000174,"about_ca_topic_score_gemma":0.0005811955,"domain_scores_codex":[0.9997197,0.00004136376,0.0000240821,0.00007289662,0.00003467104,0.0001072769],"domain_scores_gemma":[0.9996402,0.00008705439,0.000104533,0.00003521255,0.00002839718,0.0001045992],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008959845,0.00003494247,0.00006845887,0.00001022761,0.000001743704,0.00001657514,0.00001000616,0.00001164939,0.9995393,0.0000559381,0.00001459692,0.0001469942],"study_design_scores_gemma":[0.00002321149,0.0004870535,0.002166733,0.000006019635,0.00001220481,0.000181575,0.00002246191,0.0005586758,0.9956465,0.00003657026,0.0008551234,0.000003763411],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9954211,0.0002843007,0.002243784,0.0001199252,0.00003393383,0.0000283444,0.00029301,0.00009202741,0.001483582],"genre_scores_gemma":[0.9943738,0.0002508818,0.001467385,0.00009003795,0.00001860322,0.00003556792,0.0007284337,0.00008870022,0.002946662],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001372408,"threshold_uncertainty_score":0.004591107,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01830708022454413,"score_gpt":0.2627857927148814,"score_spread":0.2444787124903373,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}