{"id":"W1962293284","doi":"10.1046/j.1471-4159.2001.00152.x","title":"PC12 cells utilize the homophilic binding site of L1 for cell−cell adhesion but L1–αvβ3 interaction for neurite outgrowth","year":2001,"lang":"en","type":"article","venue":"Journal of Neurochemistry","topic":"Axon Guidance and Neuronal Signaling","field":"Neuroscience","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Medical Research Council","keywords":"Neurite; Cell biology; Integrin; Cell adhesion; Neural cell adhesion molecule; Nerve growth factor; Immunoglobulin superfamily; Chemistry; Molecular biology; Biology; Cell adhesion molecule; Cell; In vitro; Receptor; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000139738,0.0008412436,0.0007018656,0.0003182064,0.0005134766,0.0007838203,0.0004410872,0.000349315,0.002168093],"category_scores_gemma":[0.0001407966,0.0003077032,0.0006772972,0.0004396272,0.0002422476,0.0002852437,0.0004174293,0.0008893793,0.002233107],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007615195,"about_ca_system_score_gemma":0.0004083159,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.005375879,"about_ca_topic_score_gemma":0.009986045,"domain_scores_codex":[0.9996905,0.00003661271,0.0000266948,0.00007871115,0.00007776127,0.00008966304],"domain_scores_gemma":[0.9998342,0.00003096195,0.00003493838,0.00003517649,0.00002956823,0.00003521858],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000825829,0.00003322144,0.0002911941,0.00007083483,0.00001395146,0.00005666164,0.00002792909,0.00005221539,0.9970735,0.0001356401,0.0001215436,0.002040749],"study_design_scores_gemma":[0.00001912389,0.0001275386,0.005391799,0.00001426274,0.00003245738,0.0003333516,0.000035992,0.0008228571,0.9853438,0.00006730921,0.007798572,0.0000130305],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9634333,0.005279234,0.01720316,0.0002722789,0.00007995761,0.0001172274,0.00285192,0.000532914,0.01023002],"genre_scores_gemma":[0.9544799,0.003497682,0.01983172,0.000197179,0.00002792489,0.0002181952,0.006776423,0.000136155,0.01483489],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005375879,"threshold_uncertainty_score":0.0106892,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05135272790301808,"score_gpt":0.2882226223278839,"score_spread":0.2368698944248658,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}