{"id":"W1962453771","doi":"10.1002/pbc.24587","title":"Treatment with topotecan plus cyclophosphamide in children with first relapse of neuroblastoma","year":2013,"lang":"en","type":"article","venue":"Pediatric Blood & Cancer","topic":"Neuroblastoma Research and Treatments","field":"Medicine","cited_by":35,"is_retracted":false,"has_abstract":true,"ca_institutions":"Children's Hospital of Western Ontario; University of Toronto; SickKids Foundation; Children’s Health Research Institute; Hospital for Sick Children; London Health Sciences Centre","funders":"Canada Research Chairs; Pediatric Oncology Group of Ontario","keywords":"Medicine; Topotecan; Neutropenia; Neuroblastoma; Cyclophosphamide; Internal medicine; Febrile neutropenia; Chemotherapy; Surgery; Refractory (planetary science); Regimen; Salvage therapy; Hematopoietic stem cell transplantation; Transplantation; Oncology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003203887,0.0001869409,0.0005609935,0.0003620317,0.0003863421,0.0003128994,0.0004008288,0.0004385825,0.0006261915],"category_scores_gemma":[0.002072756,0.0001305704,0.0003580065,0.0005065411,0.0003617775,0.0002041899,0.0002441874,0.0006771058,0.0001158775],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001338579,"about_ca_system_score_gemma":0.0009742405,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00388131,"about_ca_topic_score_gemma":0.008289265,"domain_scores_codex":[0.9997151,0.00005039381,0.00003979831,0.00004711055,0.00008281828,0.00006469669],"domain_scores_gemma":[0.9988441,0.0002770117,0.0005654439,0.00003660153,0.00005146268,0.000225292],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.0006411746,0.0001136675,0.9326098,0.0002712743,0.0001111242,0.03143367,0.0004170379,0.0005021736,0.003080037,0.00006542782,0.001267542,0.02948708],"study_design_scores_gemma":[0.0001418779,0.001734984,0.7648557,0.0001811421,0.0001638917,0.2236606,0.0004356993,0.000664718,0.003475155,0.00009781868,0.00456934,0.0000189184],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9940674,0.004612098,0.0001490933,0.0002145435,0.00001308986,0.0000256032,0.0001909169,0.00002491621,0.0007023229],"genre_scores_gemma":[0.9969634,0.001796456,0.0004524819,0.0001634556,0.00002972591,0.00001902143,0.0004426192,0.00000974563,0.0001229719],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00388131,"threshold_uncertainty_score":0.00971216,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006616647676920826,"score_gpt":0.2321073129621447,"score_spread":0.2254906652852238,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}