{"id":"W1962453771","doi":"10.1002/pbc.24587","title":"Treatment with topotecan plus cyclophosphamide in children with first relapse of neuroblastoma","year":2013,"lang":"en","type":"article","venue":"Pediatric Blood & Cancer","topic":"Neuroblastoma Research and Treatments","field":"Medicine","cited_by":35,"is_retracted":false,"has_abstract":true,"ca_institutions":"Children's Hospital of Western Ontario; University of Toronto; SickKids Foundation; Children’s Health Research Institute; Hospital for Sick Children; London Health Sciences Centre","funders":"Canada Research Chairs; Pediatric Oncology Group of Ontario","keywords":"Medicine; Topotecan; Neutropenia; Neuroblastoma; Cyclophosphamide; Internal medicine; Febrile neutropenia; Chemotherapy; Surgery; Refractory (planetary science); Regimen; Salvage therapy; Hematopoietic stem cell transplantation; Transplantation; Oncology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000254798,0.0002854776,0.0004506054,0.0002460343,0.00005397635,0.00001606434,0.0001050424,0.00006164533,0.0002455585],"category_scores_gemma":[0.00001464644,0.0001827885,0.0000657563,0.0006906983,0.00008291109,0.0001182172,0.0000353882,0.000191201,0.00003877048],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000172034,"about_ca_system_score_gemma":0.0005975568,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.008402281,"about_ca_topic_score_gemma":0.002341205,"domain_scores_codex":[0.9983163,0.00002886082,0.0002680395,0.0004483846,0.0004337665,0.0005046052],"domain_scores_gemma":[0.9990025,0.00006703478,0.0001282218,0.000394376,0.0001056739,0.0003022018],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0007815649,0.00099131,0.9954094,0.0001019508,0.0003105884,0.000262929,0.0001335709,0.0001249569,0.00009348126,0.000003710947,0.0001918556,0.001594698],"study_design_scores_gemma":[0.01531119,0.00789002,0.9723374,0.00008238333,0.0006536543,0.0002895864,0.00001620022,0.00002858126,0.003106296,0.000006631903,0.00008762573,0.0001904085],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.996076,0.001281651,0.000002416472,0.0005690958,0.00002784265,0.00147839,0.00002935478,0.00004942491,0.0004858482],"genre_scores_gemma":[0.9946721,0.003393345,0.0002892411,0.00006677771,0.0001730481,0.0006515755,0.00001188748,0.00005433037,0.0006877596],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02307196,"threshold_uncertainty_score":0.9982008,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006616647676920826,"score_gpt":0.2321073129621447,"score_spread":0.2254906652852238,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}