{"id":"W1963115426","doi":"10.1111/cei.12593","title":"Phenotypical and functional profiles of natural killer cells exhibiting matrix metalloproteinase-mediated CD16 cleavage after anti-HIV antibody-dependent activation","year":2015,"lang":"en","type":"article","venue":"Clinical & Experimental Immunology","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre Hospitalier de l’Université de Montréal; McGill University Health Centre","funders":"National Health and Medical Research Council; Canadian Institutes of Health Research","keywords":"CD16; Immunology; Biology; Antibody-dependent cell-mediated cytotoxicity; Cytotoxic T cell; Natural killer cell; Interleukin 21; Interleukin 12; Antibody; Cell biology; T cell; Antigen; Immune system; In vitro; CD8; Monoclonal antibody; CD3","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.00050003,0.0003233866,0.0006445912,0.0001652194,0.0001390981,0.0000242784,0.0001508207,0.0005688037,0.001415025],"category_scores_gemma":[0.0003179686,0.0002838359,0.0002113694,0.0001263934,0.0007908947,0.0003671707,0.0002871487,0.0008249278,0.0008346393],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000893607,"about_ca_system_score_gemma":0.00008220906,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005485617,"about_ca_topic_score_gemma":0.000001042445,"domain_scores_codex":[0.9972173,0.0006130118,0.001072797,0.000578707,0.0001049718,0.0004132157],"domain_scores_gemma":[0.9986569,0.0003687715,0.0004321253,0.0003017923,0.0001821323,0.00005833933],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003820356,0.0008387156,0.003352954,0.00001188583,0.0003570546,0.000007030026,0.0002470005,0.000001478587,0.9875863,0.000358422,0.003011801,0.0004070303],"study_design_scores_gemma":[0.004844064,0.0009867082,0.02891672,0.00005438391,0.00005265065,0.00008157313,0.002354692,0.00002739102,0.9519172,0.00002806308,0.01040834,0.0003281717],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9827804,0.006113176,0.0003010439,0.0001860267,0.009595171,0.0004540251,0.000007289812,0.0001027741,0.0004600786],"genre_scores_gemma":[0.9940519,0.00009831451,0.0001874486,0.0002609967,0.0001198214,0.0000626402,0.0005110531,0.00003460691,0.004673191],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03566903,"threshold_uncertainty_score":0.9999614,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02839939038758674,"score_gpt":0.3220727860493143,"score_spread":0.2936733956617276,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}