{"id":"W1963128175","doi":"10.4049/jimmunol.0904043","title":"Mouse and Human Eosinophils Degranulate in Response to Platelet-Activating Factor (PAF) and LysoPAF via a PAF-Receptor–Independent Mechanism: Evidence for a Novel Receptor","year":2010,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Asthma and respiratory diseases","field":"Medicine","cited_by":84,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba; University of Alberta","funders":"National Institute of Allergy and Infectious Diseases; National Institutes of Health","keywords":"Platelet-activating factor; Degranulation; Lipid signaling; Eosinophil; Eosinophil peroxidase; Cell biology; Platelet-activating factor receptor; Immunology; Receptor; Biology; Chemistry; Inflammation; Biochemistry; Myeloperoxidase; Antagonist","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002883328,0.0004965111,0.0002044716,0.00019146,0.00008897549,0.000248841,0.000186099,0.0004224235,0.001280153],"category_scores_gemma":[0.0001266585,0.0001332369,0.0003314954,0.0001077195,0.0001448495,0.0002635774,0.0002050153,0.0004464994,0.0005125527],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009652305,"about_ca_system_score_gemma":0.00008803455,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000198129,"about_ca_topic_score_gemma":0.0003713392,"domain_scores_codex":[0.9997259,0.00006361544,0.00003279192,0.00005062417,0.00006530563,0.00006180933],"domain_scores_gemma":[0.9999197,0.00001501228,0.00002340096,0.00001448466,0.000008160159,0.00001936278],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00016243,0.00002710621,0.0001802558,0.00002309035,0.000004775158,0.00006803637,0.00001027738,0.00001196341,0.9983871,0.00004983056,0.0000182424,0.001056858],"study_design_scores_gemma":[0.00009183971,0.001035962,0.01383474,0.000009501005,0.00004365272,0.001738257,0.00003600682,0.0004276411,0.979627,0.00005154665,0.003097452,0.000006357236],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9889454,0.003957442,0.004900193,0.0001259255,0.00002207391,0.0001017978,0.0004649903,0.00006753778,0.001414601],"genre_scores_gemma":[0.9870072,0.003141751,0.005508529,0.0001201329,0.00003188597,0.0001563935,0.001184335,0.00001780097,0.002832004],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001280153,"threshold_uncertainty_score":0.004282534,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03657453552221298,"score_gpt":0.3135335412297064,"score_spread":0.2769590057074934,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}