{"id":"W1963558935","doi":"10.1523/jneurosci.2840-11.2011","title":"Functional Recovery after Peripheral Nerve Injury is Dependent on the Pro-Inflammatory Cytokines IL-1β and TNF: Implications for Neuropathic Pain","year":2011,"lang":"en","type":"article","venue":"Journal of Neuroscience","topic":"Pain Mechanisms and Treatments","field":"Medicine","cited_by":341,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta; McGill University; Université Laval; Centre hospitalier de l'Université Laval","funders":"Canadian Institutes of Health Research","keywords":"Sciatic nerve; Peripheral nerve injury; Neuropathic pain; Nerve injury; Medicine; Tumor necrosis factor alpha; Sciatic nerve injury; Allodynia; Nociception; Cytokine; Axon; Inflammation; Anesthesia; Receptor; Hyperalgesia; Immunology; Internal medicine; Anatomy","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001083296,0.0001070955,0.0001327299,0.00008063435,0.0001638672,0.00003365671,0.00009662132,0.00003182978,0.00002463211],"category_scores_gemma":[0.0004967149,0.0000625067,0.00009949306,0.00009193301,0.00008118583,0.0001615716,0.00002751978,0.0001636707,0.000001660331],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003280271,"about_ca_system_score_gemma":0.0001065725,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00000127764,"about_ca_topic_score_gemma":7.96331e-7,"domain_scores_codex":[0.9990401,0.0001351834,0.0002490401,0.0001843526,0.0002351535,0.0001562083],"domain_scores_gemma":[0.999231,0.0001513769,0.0001975594,0.0001726926,0.0001338782,0.0001135268],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.004464858,0.001075494,0.1156598,0.0001122124,0.00006527058,0.0004291807,0.0008663246,0.0000133501,0.8218831,0.00211951,0.003947193,0.04936378],"study_design_scores_gemma":[0.0006303542,0.003737453,0.9830956,0.00008464308,0.00007314394,0.0007254163,0.00004114253,0.0003889145,0.006447254,0.002657337,0.002014595,0.0001041485],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.989878,0.00006269495,0.005720617,0.003498684,0.0004259991,0.0003211392,0.00002530141,0.000008634715,0.00005895427],"genre_scores_gemma":[0.9928597,0.00006822657,0.0004133174,0.0061556,0.0001315074,0.00004278816,2.873776e-7,0.00001173516,0.0003168325],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.8674358,"threshold_uncertainty_score":0.2548949,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04914488783880235,"score_gpt":0.2714479837749269,"score_spread":0.2223030959361246,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}