{"id":"W1963570892","doi":"10.1186/2045-7022-4-s3-p27","title":"The predictive value of the <i>in vitro</i> platelet toxicity assay (iPTA) for the diagnosis of hypersensitivity reactions to sulfonamides: a case‐control study","year":2014,"lang":"en","type":"article","venue":"Clinical and Translational Allergy","topic":"Drug-Induced Adverse Reactions","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"","keywords":"Medicine; Toxicity; Drug; In vitro; Predictive value; Drug reaction; Pharmacology; Adverse effect; Platelet; Internal medicine; Chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001845118,0.0001197974,0.0003499345,0.00003567418,0.0002496888,0.000007111733,0.00008583441,0.0000872571,0.000001803264],"category_scores_gemma":[0.001498658,0.00006172528,0.0002627517,0.0001852016,0.000294451,0.00004791714,0.00002009591,0.0002821918,7.597548e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001296608,"about_ca_system_score_gemma":0.00009853463,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00023605,"about_ca_topic_score_gemma":0.001064494,"domain_scores_codex":[0.9983013,0.0004103778,0.0006208817,0.0002440441,0.0002696406,0.0001537441],"domain_scores_gemma":[0.98445,0.01486573,0.0001480268,0.0002796421,0.0001711747,0.00008546434],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.007340265,0.01315563,0.1740303,0.0001674405,0.007122477,0.00007616041,0.004472271,0.0210583,0.009896368,0.02895924,0.0002610299,0.7334605],"study_design_scores_gemma":[0.004227384,0.0002894123,0.9611283,0.00005258313,0.0003133223,0.00007959241,0.0008187727,0.01775184,0.0006099583,0.001017516,0.01362098,0.00009033357],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9777401,0.00005815161,0.003398355,0.01527709,0.0003189524,0.001899552,0.0003334719,0.00001372559,0.0009606105],"genre_scores_gemma":[0.9990876,0.00004717556,0.0001332007,0.0003300151,0.0001567556,0.000169713,0.000003578279,0.00001112559,0.0000608879],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.787098,"threshold_uncertainty_score":0.2517084,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03746001253729962,"score_gpt":0.3242909959248654,"score_spread":0.2868309833875657,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}