{"id":"W1963620603","doi":"10.1006/bbrc.2001.4503","title":"RNase Activity of a DNA Minor Groove Binder with a Minimalist Catalytic Motif from RNase A","year":2001,"lang":"en","type":"article","venue":"Biochemical and Biophysical Research Communications","topic":"DNA and Nucleic Acid Chemistry","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"Centre National de la Recherche Scientifique","keywords":"Netropsin; Cleavage (geology); RNase P; Imidazole; DNA; Chemistry; RNase H; Stereochemistry; Cleave; RNA; Nucleic acid; Biochemistry; Biology; Minor groove","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006015672,0.0003985524,0.0005742383,0.0002657071,0.000299427,0.0005840809,0.0006270727,0.0006084107,0.001697206],"category_scores_gemma":[0.0007634974,0.0002117848,0.0003748126,0.000259183,0.000296197,0.0002403849,0.0003322341,0.0007708663,0.0004762413],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005635386,"about_ca_system_score_gemma":0.000384243,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001044774,"about_ca_topic_score_gemma":0.000802147,"domain_scores_codex":[0.999554,0.00008879023,0.00003754222,0.0001012935,0.0001275893,0.00009077897],"domain_scores_gemma":[0.9996589,0.0001042662,0.00004603561,0.00003751399,0.00003901451,0.0001143579],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008341672,0.0001714648,0.0005040716,0.00005469238,0.00002016002,0.0001221616,0.0000342753,0.0005256832,0.9948069,0.0003535401,0.00009435921,0.0024785],"study_design_scores_gemma":[0.00006927941,0.0003976694,0.000974704,0.000007701588,0.00001951785,0.0003267755,0.0000150131,0.002167389,0.9946872,0.00008547428,0.001238175,0.00001101915],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9965894,0.0004826639,0.00216453,0.00005042825,0.00002548468,0.00001393178,0.0000953382,0.00007587495,0.0005022751],"genre_scores_gemma":[0.9962466,0.0001558676,0.001867277,0.00003374933,0.00001266012,0.00001029132,0.0005517638,0.00002339925,0.00109832],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001697206,"threshold_uncertainty_score":0.00567776,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04661999454491514,"score_gpt":0.3308950349120254,"score_spread":0.2842750403671103,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}