{"id":"W1963633705","doi":"10.1074/jbc.m106422200","title":"Structural and Functional Interactions of Transcription Factor (TF) IIA with TFIIE and TFIIF in Transcription Initiation by RNA Polymerase II","year":2001,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Montreal Clinical Research Institute","funders":"Canadian Institutes of Health Research","keywords":"Transcription factor II A; Transcription factor II F; Transcription factor II E; Transcription factor II B; General transcription factor; Transcription preinitiation complex; RNA polymerase II; Transcription factor II H; Cell biology; RNA polymerase II holoenzyme; Biology; Molecular biology; Transcription factor II D; Transcription factor; Chemistry; Promoter; Genetics; Transcriptional regulation; Gene; Gene expression","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006631974,0.000111009,0.0001572121,0.00002508949,0.00004741427,0.00001170176,0.00004628916,0.0001337545,0.00005228693],"category_scores_gemma":[0.00001993401,0.00008224296,0.00004882939,0.00004897819,0.00008805508,0.00001393702,0.00001424108,0.0001475513,4.791582e-8],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001873063,"about_ca_system_score_gemma":0.0000258642,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000005197815,"about_ca_topic_score_gemma":0.00000794648,"domain_scores_codex":[0.9993613,0.00002163221,0.0003044022,0.0001358412,0.00007706512,0.00009975819],"domain_scores_gemma":[0.999603,0.0000105411,0.0001976074,0.00005473494,0.00007019546,0.00006393523],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004118947,0.00005637639,0.008365204,0.00001841677,0.0000291917,0.000002611384,0.00005130777,0.00002818209,0.9899521,0.000003659273,0.0000235407,0.001057509],"study_design_scores_gemma":[0.002193989,0.0009372419,0.09447812,0.00005473325,0.0000361333,0.0006338762,0.0003312792,0.0003868387,0.9000286,0.0001539285,0.0005422818,0.0002229326],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9982999,0.0008478826,0.000505855,0.0001458171,0.00004173424,0.00004171977,0.00004565627,0.000001839858,0.00006957087],"genre_scores_gemma":[0.9988052,0.000739879,0.0001937461,0.00003698897,0.00008095679,0.000001532712,0.00009566494,0.000005423139,0.00004056485],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.08992346,"threshold_uncertainty_score":0.3353771,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01487595133743334,"score_gpt":0.2240354070431865,"score_spread":0.2091594557057532,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}