{"id":"W1963633705","doi":"10.1074/jbc.m106422200","title":"Structural and Functional Interactions of Transcription Factor (TF) IIA with TFIIE and TFIIF in Transcription Initiation by RNA Polymerase II","year":2001,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Montreal Clinical Research Institute","funders":"Canadian Institutes of Health Research","keywords":"Transcription factor II A; Transcription factor II F; Transcription factor II E; Transcription factor II B; General transcription factor; Transcription preinitiation complex; RNA polymerase II; Transcription factor II H; Cell biology; RNA polymerase II holoenzyme; Biology; Molecular biology; Transcription factor II D; Transcription factor; Chemistry; Promoter; Genetics; Transcriptional regulation; Gene; Gene expression","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003367283,0.0003373592,0.0001643283,0.00022072,0.0004834459,0.0006171374,0.0003019966,0.0003603634,0.0007250782],"category_scores_gemma":[0.0004592588,0.0002470639,0.0002202619,0.0001764513,0.0004569061,0.000348658,0.000173414,0.0002869153,0.0004528122],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005134448,"about_ca_system_score_gemma":0.000210026,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005024586,"about_ca_topic_score_gemma":0.0004294962,"domain_scores_codex":[0.9999013,0.0000321591,0.000005143995,0.00001764109,0.00001856527,0.00002513613],"domain_scores_gemma":[0.999887,0.00002547369,0.00001970336,0.000009084744,0.00001683618,0.00004191091],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007010859,0.00007080584,0.004548735,0.0001515071,0.00001882718,0.0004479886,0.0001170843,0.006934393,0.9706927,0.009633636,0.0001582157,0.006524931],"study_design_scores_gemma":[0.0001444488,0.0008806843,0.04239677,0.0000860504,0.0001293693,0.001696669,0.0004655342,0.07736883,0.85041,0.01199421,0.01434929,0.00007806739],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9822116,0.003992079,0.01088965,0.0002053929,0.0000355804,0.00001275796,0.0000620857,0.00006706946,0.002523748],"genre_scores_gemma":[0.9970655,0.0006382989,0.001493711,0.0000127959,0.00001325666,0.00001020654,0.00006739151,0.000003173127,0.000695656],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007250782,"threshold_uncertainty_score":0.00372535,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01487595133743334,"score_gpt":0.2240354070431865,"score_spread":0.2091594557057532,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}