{"id":"W1963703398","doi":"10.1038/nbt1011","title":"Protein sequencing by mass analysis of polypeptide ladders after controlled protein hydrolysis","year":2004,"lang":"en","type":"letter","venue":"Nature Biotechnology","topic":"Advanced Proteomics Techniques and Applications","field":"Chemistry","cited_by":118,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"Natural Sciences and Engineering Research Council of Canada; Genome Prairie; Genome Canada","keywords":"Biochemistry; Peptide sequence; Amino acid; Protein sequencing; Hydrolysate; Chemistry; Escherichia coli; Biology; Hydrolysis; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001262074,0.001549768,0.001143421,0.001023502,0.0008272171,0.0008173441,0.001337158,0.002913627,0.002377533],"category_scores_gemma":[0.0025083,0.0007492811,0.000772895,0.0007691588,0.001128178,0.001354859,0.0006690316,0.004311571,0.003851097],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006036538,"about_ca_system_score_gemma":0.0003206839,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002792929,"about_ca_topic_score_gemma":0.000789278,"domain_scores_codex":[0.9991093,0.0002665671,0.0001233624,0.0001695275,0.0002309634,0.0001002563],"domain_scores_gemma":[0.99769,0.0008728806,0.0002093603,0.0004679716,0.0005903158,0.0001696333],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006431157,0.0001507037,0.0002898241,0.0003712426,0.00004648587,0.001126368,0.0001259865,0.0001290881,0.963116,0.002047667,0.01151462,0.02043891],"study_design_scores_gemma":[0.000143011,0.0003161873,0.002514692,0.00003890585,0.00007568835,0.004531081,0.00003458467,0.005691425,0.938306,0.005489177,0.0427851,0.00007396592],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"empirical","genre_scores_codex":[0.1426846,0.01309991,0.7732076,0.03741753,0.0127852,0.0009310005,0.001409828,0.005964,0.01250045],"genre_scores_gemma":[0.2983926,0.01626312,0.6101838,0.02902415,0.003482395,0.00166676,0.004511911,0.001668328,0.034807],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.002913627,"threshold_uncertainty_score":0.007953644,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003860537422706217,"score_gpt":0.2302112252846995,"score_spread":0.2263506878619933,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}