{"id":"W1963742875","doi":"10.1002/gene.10092","title":"Expression of Cre recombinase in the developing mouse limb bud driven by a <i>Prxl</i> enhancer","year":2002,"lang":"en","type":"article","venue":"genesis","topic":"Developmental Biology and Gene Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1039,"is_retracted":false,"has_abstract":true,"ca_institutions":"Health Sciences Centre; Lunenfeld-Tanenbaum Research Institute; University of Toronto; Sunnybrook Health Science Centre; Mount Sinai Hospital","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institute of Dental and Craniofacial Research; University of Alabama","keywords":"Limb bud; Cre recombinase; Biology; Mesenchyme; Enhancer; Transgene; Limb development; Genetically modified mouse; Reporter gene; Cell biology; Molecular biology; Gene expression; Genetics; Gene; Mesenchymal stem cell","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00038614,0.0002970429,0.0002398926,0.000294594,0.0002115622,0.000391183,0.0005036519,0.0003921097,0.002044138],"category_scores_gemma":[0.0001751293,0.0004255652,0.0002754663,0.000179841,0.0003242813,0.0003467336,0.0002813613,0.0008330711,0.001702218],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002709022,"about_ca_system_score_gemma":0.0002559698,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004773942,"about_ca_topic_score_gemma":0.0005067301,"domain_scores_codex":[0.9997638,0.00002677567,0.00002863278,0.0000641431,0.00007320623,0.00004352724],"domain_scores_gemma":[0.9998193,0.00003250944,0.00004975612,0.00003220174,0.00002022058,0.00004601899],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001931755,0.00000687384,0.00003963695,0.00001837568,0.000001012448,0.00002894423,0.000009336572,0.00002942676,0.9987774,0.0001751934,0.00002610913,0.0008682018],"study_design_scores_gemma":[0.00002713774,0.0001190657,0.0009026172,0.000009904234,0.00001020381,0.0003780889,0.00001022538,0.0003709505,0.9912065,0.00004527413,0.006917245,0.000002831409],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8545334,0.004405278,0.1236196,0.0004786355,0.0001783563,0.0004239569,0.00209116,0.001656028,0.01261355],"genre_scores_gemma":[0.8697742,0.003721594,0.09766352,0.0001662498,0.00005845315,0.0002774626,0.002640192,0.0003745833,0.0253239],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002044138,"threshold_uncertainty_score":0.006838322,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01100798310570987,"score_gpt":0.2256621303805343,"score_spread":0.2146541472748244,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}