{"id":"W1963764537","doi":"10.1161/strokeaha.114.006573","title":"Alteplase for Acute Ischemic Stroke","year":2015,"lang":"en","type":"article","venue":"Stroke","topic":"Acute Ischemic Stroke Management","field":"Medicine","cited_by":89,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"Medical Research Council; National Institutes of Health; National Health and Medical Research Council; Scottish Funding Council; Norges Forskningsråd; Dalhousie University; Schweizerische Herzstiftung; National Research Foundation; Karolinska Institutet; Stroke Association; Chest Heart and Stroke Scotland; Stockholms Läns Landsting; National Institute for Health and Care Research; National Institute for Social Care and Health Research","keywords":"Medicine; Thrombolysis; Randomization; Stroke (engine); Tissue plasminogen activator; Internal medicine; T-plasminogen activator; Randomized controlled trial; Odds ratio; Plasminogen activator; Intracerebral hemorrhage; Thrombus; Atrial fibrillation; Fibrinolytic agent; Cardiology; Surgery; Myocardial infarction; Subarachnoid hemorrhage","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00079235,0.0003020027,0.0006450806,0.0002069181,0.0001430709,0.0003097845,0.000219829,0.000285241,0.002609121],"category_scores_gemma":[0.0007361826,0.00005251318,0.0004407453,0.0002508228,0.0001830422,0.0001762305,0.0001680889,0.0008864077,0.0003140473],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002494075,"about_ca_system_score_gemma":0.000511976,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003422907,"about_ca_topic_score_gemma":0.0007038265,"domain_scores_codex":[0.9996848,0.0001518572,0.00004331717,0.00003513493,0.0000417111,0.00004323096],"domain_scores_gemma":[0.9997359,0.00008930101,0.00007297938,0.00001326935,0.00001823351,0.00007032952],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.262239,0.005357843,0.03146497,0.005544124,0.003646407,0.0006752596,0.0001456206,0.00109482,0.0103987,0.001802319,0.01185887,0.665772],"study_design_scores_gemma":[0.437936,0.203451,0.2742539,0.002691936,0.006503371,0.005853919,0.0002458007,0.002548969,0.01200328,0.005045128,0.04939732,0.00006950454],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"review","genre_scores_codex":[0.9074394,0.07865236,0.000968491,0.002458116,0.0005881577,0.000754012,0.001140532,0.00005863065,0.007940437],"genre_scores_gemma":[0.9799626,0.01383787,0.00100459,0.001743505,0.0005577769,0.0005197183,0.0008652185,0.000005172484,0.001503424],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.002609121,"threshold_uncertainty_score":0.008728445,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02671670262256854,"score_gpt":0.3032640151802236,"score_spread":0.2765473125576551,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}