{"id":"W1963764537","doi":"10.1161/strokeaha.114.006573","title":"Alteplase for Acute Ischemic Stroke","year":2015,"lang":"en","type":"article","venue":"Stroke","topic":"Acute Ischemic Stroke Management","field":"Medicine","cited_by":89,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"Medical Research Council; National Institutes of Health; National Health and Medical Research Council; Scottish Funding Council; Norges Forskningsråd; Dalhousie University; Schweizerische Herzstiftung; National Research Foundation; Karolinska Institutet; Stroke Association; Chest Heart and Stroke Scotland; Stockholms Läns Landsting; National Institute for Health and Care Research; National Institute for Social Care and Health Research","keywords":"Medicine; Thrombolysis; Randomization; Stroke (engine); Tissue plasminogen activator; Internal medicine; T-plasminogen activator; Randomized controlled trial; Odds ratio; Plasminogen activator; Intracerebral hemorrhage; Thrombus; Atrial fibrillation; Fibrinolytic agent; Cardiology; Surgery; Myocardial infarction; Subarachnoid hemorrhage","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000232805,0.0002350392,0.000379052,0.0001288441,0.0000467214,0.00002291823,0.0001896991,0.0001102932,0.00009819547],"category_scores_gemma":[0.000176797,0.0002118438,0.0001974657,0.0000969225,0.00007078001,0.00009816683,0.0001324795,0.0001937771,0.0002337933],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001704652,"about_ca_system_score_gemma":0.0001473896,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001375139,"about_ca_topic_score_gemma":0.00000208446,"domain_scores_codex":[0.9983928,0.00001119284,0.0002909353,0.0003979528,0.000419351,0.0004877674],"domain_scores_gemma":[0.9987102,0.00005246254,0.00009940634,0.0005572495,0.0001792291,0.000401467],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0006186868,0.00009510063,0.003000098,0.00004800889,0.0006248154,0.00006134999,0.0001280849,0.000003233484,0.04946142,0.0001436583,0.9420142,0.003801368],"study_design_scores_gemma":[0.006145213,0.000607029,0.0002674523,0.0000323928,0.0008302449,0.00008448287,0.0004905346,0.0005165521,0.09115993,0.0000161611,0.8996118,0.0002382318],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.6347156,0.0004250692,0.0121812,0.004152042,0.0009718096,0.001772426,0.0006295076,0.0003679623,0.3447844],"genre_scores_gemma":[0.7335637,0.0000424036,0.0381436,0.002565344,0.001171052,0.0003216605,0.0003174836,0.0001044573,0.2237703],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1210142,"threshold_uncertainty_score":0.863874,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02671670262256854,"score_gpt":0.3032640151802236,"score_spread":0.2765473125576551,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}