{"id":"W1963811389","doi":"10.1371/journal.pone.0056721","title":"Global and Stage Specific Patterns of Krüppel-Associated-Box Zinc Finger Protein Gene Expression in Murine Early Embryonic Cells","year":2013,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":47,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Hospital for Sick Children; École Polytechnique Fédérale de Lausanne; Wellcome Trust; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; National Science Foundation","keywords":"Biology; Zinc finger; Embryonic stem cell; Induced pluripotent stem cell; Polycomb-group proteins; Chromatin; Genomic imprinting; Gene silencing; Krüppel; Genetics; Gene; Transcription factor; Regulation of gene expression; Stem cell; KLF4; Cell biology; Gene expression; DNA methylation; Repressor","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007851797,0.0001554321,0.0001215128,0.0005362991,0.000107755,0.0002276879,0.0001176827,0.0001486941,0.0005239245],"category_scores_gemma":[0.0001180991,0.0001449635,0.0001169961,0.0001962412,0.0001372931,0.0001298156,0.0001613404,0.0002398226,0.00034158],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002005856,"about_ca_system_score_gemma":0.00009239143,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004370039,"about_ca_topic_score_gemma":0.0007780382,"domain_scores_codex":[0.9998882,0.000009879434,0.00001145712,0.00004312045,0.00002300148,0.00002430632],"domain_scores_gemma":[0.9998937,0.00001898881,0.00003016966,0.00001576368,0.00001362777,0.00002785927],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004542689,0.00000488645,0.0008906075,0.00001102119,0.000002612156,0.00001880818,0.00002210287,0.00006116379,0.9975146,0.00009806119,0.00001504692,0.001315622],"study_design_scores_gemma":[0.00002417932,0.0003075762,0.1094866,0.00001698012,0.00003613112,0.0005586753,0.00007371304,0.001333682,0.8831078,0.0003256146,0.004709768,0.00001932697],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9916181,0.001937698,0.00365546,0.0000286974,0.000005010428,0.00001953084,0.001174771,0.00008965915,0.001471264],"genre_scores_gemma":[0.9903099,0.0009356886,0.004212048,0.000049144,0.000006667416,0.00003882801,0.001479024,0.00003797757,0.002930755],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005362991,"threshold_uncertainty_score":0.001752675,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009771489140085856,"score_gpt":0.1877868652634134,"score_spread":0.1780153761233275,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}