{"id":"W1963811389","doi":"10.1371/journal.pone.0056721","title":"Global and Stage Specific Patterns of Krüppel-Associated-Box Zinc Finger Protein Gene Expression in Murine Early Embryonic Cells","year":2013,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":47,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Hospital for Sick Children; École Polytechnique Fédérale de Lausanne; Wellcome Trust; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; National Science Foundation","keywords":"Biology; Zinc finger; Embryonic stem cell; Induced pluripotent stem cell; Polycomb-group proteins; Chromatin; Genomic imprinting; Gene silencing; Krüppel; Genetics; Gene; Transcription factor; Regulation of gene expression; Stem cell; KLF4; Cell biology; Gene expression; DNA methylation; Repressor","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008009138,0.0001351225,0.0001911992,0.00002492469,0.00002504043,0.00002514265,0.0001357704,0.0001401719,0.00005397486],"category_scores_gemma":[0.00001335055,0.0001348788,0.00003566583,0.00004880887,0.00002840928,0.000004941073,0.000171247,0.00006679868,0.00000842584],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002974663,"about_ca_system_score_gemma":0.00002291572,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001311966,"about_ca_topic_score_gemma":0.0001168357,"domain_scores_codex":[0.999114,0.00003838463,0.0002210597,0.0002686553,0.0001348272,0.0002231115],"domain_scores_gemma":[0.9994776,0.000004388438,0.0001314819,0.0002648267,0.00005947744,0.0000621832],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001389673,0.0004561514,0.04816739,0.00006758574,0.00004121662,0.000002053358,0.00003212471,0.00001450377,0.9510813,0.000006974541,0.00003074824,0.00008603729],"study_design_scores_gemma":[0.0006282094,0.0002109251,0.1322923,0.000115625,0.00001016066,4.030831e-7,0.00002530496,0.0001571089,0.8663148,0.00005782234,0.00003024603,0.0001570004],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9988683,0.0003444499,0.0000813271,0.00003892495,0.00001697315,0.0003994123,0.0001258899,0.000006387329,0.0001183118],"genre_scores_gemma":[0.9966579,0.000233827,0.002086255,0.00001923049,0.00003996348,0.00003529946,0.00006006138,0.00001842611,0.0008490482],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.08476646,"threshold_uncertainty_score":0.5500199,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009771489140085856,"score_gpt":0.1877868652634134,"score_spread":0.1780153761233275,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}