{"id":"W1963819143","doi":"10.1021/bi0107400","title":"Alternate Substrate Binding Modes to Two Mutant (D98N and H255N) Forms of Nitrite Reductase from <i>Alcaligenes faecalis</i> S-6:  Structural Model of a Transient Catalytic Intermediate<sup>,</sup>","year":2001,"lang":"en","type":"article","venue":"Biochemistry","topic":"Amino Acid Enzymes and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":69,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Nitrite reductase; Nitrite; Alcaligenes faecalis; Chemistry; Active site; Stereochemistry; Oxidoreductase; Crystallography; Ligand (biochemistry); Protonation; Catalysis; Inorganic chemistry; Enzyme; Organic chemistry; Biochemistry; Nitrate; Bacteria","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007892378,0.0003190542,0.0002330701,0.00006206683,0.0001492142,0.0002659401,0.0005784509,0.000418272,0.0005584927],"category_scores_gemma":[0.0001798873,0.0001896517,0.0002262494,0.0001001444,0.0002285378,0.0001553868,0.000130812,0.0005425942,0.0001301755],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005993393,"about_ca_system_score_gemma":0.0001982082,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004363962,"about_ca_topic_score_gemma":0.003579236,"domain_scores_codex":[0.9999386,0.000008882951,0.000004101678,0.00001494631,0.0000223129,0.0000111961],"domain_scores_gemma":[0.9999183,0.0000137903,0.00002464551,0.000005474208,0.00001391989,0.00002373669],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"simulation_or_modeling","study_design_scores_codex":[0.0006000727,0.00009394498,0.002342956,0.00006361548,0.00002310178,0.0005005766,0.0001322578,0.002442133,0.9922153,0.0003128464,0.0001419612,0.001131248],"study_design_scores_gemma":[0.0002262545,0.001093019,0.02936941,0.00002760767,0.00008259729,0.001356202,0.0004848852,0.0413409,0.9217094,0.0003850654,0.003867003,0.00005773015],"study_design_candidate":"simulation_or_modeling","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9991934,0.00006030094,0.0004079018,0.00002575865,0.000003169209,0.000002952191,0.00005287196,0.00002405537,0.0002297054],"genre_scores_gemma":[0.9980195,0.00006961466,0.001218307,0.00001865494,0.000001467379,0.000006375738,0.0003390847,0.00001283864,0.0003143051],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004363962,"threshold_uncertainty_score":0.008677125,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01171547447575181,"score_gpt":0.2481991369968587,"score_spread":0.2364836625211069,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}