{"id":"W1963867217","doi":"10.1529/biophysj.105.069583","title":"Lifetime Measurements Reveal Kinetic Differences between Homophilic Cadherin Bonds","year":2005,"lang":"en","type":"article","venue":"Biophysical Journal","topic":"Cellular Mechanics and Interactions","field":"Biochemistry, Genetics and Molecular Biology","cited_by":83,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"National Institute of General Medical Sciences; National Heart, Lung, and Blood Institute; National Institutes of Health","keywords":"Cadherin; Dissociation (chemistry); Chemistry; Kinetic energy; Cleavage (geology); Molecule; Biophysics; Cell adhesion molecule; Cell; Cell biology; Biology; Biochemistry; Physics; Physical chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001184121,0.0001590277,0.0001696552,0.00004058311,0.0001485101,0.00007478176,0.0002385918,0.0001009643,0.0001048714],"category_scores_gemma":[0.00003344105,0.000134658,0.0001562433,0.00007284764,0.00003753147,0.000008318138,0.00007656551,0.0002401542,0.00009486742],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002922214,"about_ca_system_score_gemma":0.00004289588,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000006688608,"about_ca_topic_score_gemma":0.000003508533,"domain_scores_codex":[0.9989376,0.00006076023,0.0002590969,0.0002228849,0.0002532735,0.0002663616],"domain_scores_gemma":[0.9993927,0.000007466732,0.0001080143,0.0001951991,0.00009138376,0.0002052568],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001878941,0.00010519,0.0008534271,0.000002530138,0.00006940225,0.000002212862,0.00001200256,0.000005832713,0.9917809,0.00004390762,0.002033137,0.005072676],"study_design_scores_gemma":[0.0008909463,0.001122045,0.02105761,0.000041817,0.0000987418,0.0001231273,0.00002342077,0.0002958066,0.9013667,0.0001326717,0.07438143,0.0004657684],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9969075,0.0001374144,0.00123333,0.000645916,0.0001948012,0.00006507439,0.00001224676,0.000009014315,0.000794675],"genre_scores_gemma":[0.9942607,0.00006418669,0.0004095446,0.0001617514,0.003780772,0.000004628489,0.00002458732,0.00001915696,0.001274718],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.09041427,"threshold_uncertainty_score":0.5491195,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02775754731691128,"score_gpt":0.2667271991028887,"score_spread":0.2389696517859774,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}