{"id":"W1963936136","doi":"10.1074/jbc.m505323200","title":"Dynamic Changes in Histone H3 Lysine 9 Methylations","year":2005,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":83,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Histone H3; EZH2; Biology; Histone methylation; Histone; Epigenetics; Mitosis; Histone methyltransferase; PRC2; Histone H2A; Heterochromatin; Cell biology; Epigenomics; Demethylase; Genetics; Chromatin; DNA methylation; Gene expression; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001201297,0.0001022539,0.0001017762,0.0001807635,0.0001035059,0.0002423629,0.000157809,0.0001899531,0.001148235],"category_scores_gemma":[0.0002326879,0.0001064858,0.0001044304,0.000147121,0.0001650802,0.0002077614,0.00014471,0.0002772839,0.0001928528],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002200289,"about_ca_system_score_gemma":0.00009675398,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005994507,"about_ca_topic_score_gemma":0.0007504681,"domain_scores_codex":[0.9999208,0.000005686722,0.000004513204,0.00002878003,0.00002521588,0.00001483412],"domain_scores_gemma":[0.9998748,0.00002261389,0.00004211045,0.00001673564,0.00002508621,0.00001868745],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005765929,0.000003555823,0.001353921,0.00001024155,0.000005409891,0.00001815852,0.00001505852,0.00005596114,0.9965599,0.0001002707,0.00001530686,0.001804578],"study_design_scores_gemma":[0.00000873464,0.0001023801,0.06892635,0.00000365185,0.00001669868,0.0002406488,0.00006703953,0.001334358,0.9274408,0.0002881629,0.001564091,0.000007153789],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9926547,0.0007429511,0.00507061,0.00004837678,0.00001040398,0.000007192959,0.0003190308,0.00005832288,0.001088467],"genre_scores_gemma":[0.9979433,0.0001876326,0.0009570506,0.00001818072,0.000002678087,0.000005128539,0.0001375758,0.000007001918,0.000741433],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001148235,"threshold_uncertainty_score":0.003841221,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01818767399378583,"score_gpt":0.3012241498505136,"score_spread":0.2830364758567278,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}