{"id":"W1963936136","doi":"10.1074/jbc.m505323200","title":"Dynamic Changes in Histone H3 Lysine 9 Methylations","year":2005,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":83,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Histone H3; EZH2; Biology; Histone methylation; Histone; Epigenetics; Mitosis; Histone methyltransferase; PRC2; Histone H2A; Heterochromatin; Cell biology; Epigenomics; Demethylase; Genetics; Chromatin; DNA methylation; Gene expression; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003505222,0.0001120278,0.000186499,0.00003731677,0.00002758885,0.000009313609,0.0001596595,0.0002231501,0.0001023689],"category_scores_gemma":[0.000231433,0.0000873709,0.00009640626,0.00009756776,0.00006243633,0.000003298429,0.00004672525,0.0001646332,0.000002720578],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005047018,"about_ca_system_score_gemma":0.00004026163,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000001391177,"about_ca_topic_score_gemma":0.00001857998,"domain_scores_codex":[0.9992009,0.00003913443,0.0003428214,0.000153686,0.000105994,0.000157448],"domain_scores_gemma":[0.99942,0.00002470217,0.0002331494,0.0001367051,0.000106547,0.00007888363],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004537053,0.00009043661,0.002278912,0.000006072702,0.00001567045,0.000004085784,0.00001199471,0.0003549754,0.9898462,0.000002391201,0.0000566327,0.007287299],"study_design_scores_gemma":[0.0004772573,0.0001896965,0.008748581,0.00001334648,0.00001066822,0.0000220676,0.00002888137,0.000139445,0.9554929,0.0001687133,0.03457547,0.0001329328],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9912201,0.005982643,0.0008351119,0.0009800791,0.00005150001,0.000037326,0.000005834212,0.000003383539,0.0008840911],"genre_scores_gemma":[0.9940019,0.001787089,0.00339092,0.00008385066,0.0003183518,0.000002447962,0.00003711895,0.000007589216,0.0003707537],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03451884,"threshold_uncertainty_score":0.3562882,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01818767399378583,"score_gpt":0.3012241498505136,"score_spread":0.2830364758567278,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}