{"id":"W1963944722","doi":"10.3389/fonc.2013.00146","title":"Telomeres, A Busy Platform for Cell Signaling","year":2013,"lang":"en","type":"article","venue":"Frontiers in Oncology","topic":"Telomeres, Telomerase, and Senescence","field":"Medicine","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"Biotechnology and Biological Sciences Research Council; Engineering and Physical Sciences Research Council; Medical Research Council; Wellcome Trust","keywords":"Telomere; Telomerase; Shelterin; Biology; Ribonucleoprotein; Cell biology; Telomerase RNA component; Telomerase reverse transcriptase; Senescence; DNA; Genetics; RNA; DNA-binding protein; Transcription factor; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002586583,0.0002115575,0.0006425221,0.0003534554,0.00007856444,0.00001695161,0.0001871614,0.0003187835,0.0002368559],"category_scores_gemma":[0.0001522737,0.0001916553,0.0001228871,0.0002745485,0.0001432829,0.0001430682,0.00004116926,0.0003161848,0.00007561188],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003715391,"about_ca_system_score_gemma":0.000301613,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002186327,"about_ca_topic_score_gemma":0.00005030688,"domain_scores_codex":[0.9983248,0.00003469982,0.0004539847,0.0003934796,0.0001644075,0.0006286021],"domain_scores_gemma":[0.9990688,0.0001908456,0.0001244706,0.0002822355,0.0001186223,0.0002150369],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001122545,0.001109536,0.181691,0.0004861967,0.0001225332,0.0001804002,0.001890591,0.00003042783,0.02615499,0.0003204274,0.4235381,0.3633532],"study_design_scores_gemma":[0.01674955,0.00418749,0.03499267,0.0002359762,0.0002077457,0.0001669485,0.01228426,0.006327516,0.02907788,0.005859179,0.8888659,0.001044839],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9665946,0.002364921,0.01352908,0.001885894,0.00252581,0.002127944,0.00001446038,0.0001295914,0.01082774],"genre_scores_gemma":[0.8601145,0.0002988527,0.130769,0.002425783,0.0004830506,0.0004454284,0.00006189845,0.00005890031,0.005342619],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4653278,"threshold_uncertainty_score":0.7815475,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01995877951791613,"score_gpt":0.2788860529699723,"score_spread":0.2589272734520562,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}