{"id":"W1963944722","doi":"10.3389/fonc.2013.00146","title":"Telomeres, A Busy Platform for Cell Signaling","year":2013,"lang":"en","type":"article","venue":"Frontiers in Oncology","topic":"Telomeres, Telomerase, and Senescence","field":"Medicine","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"Biotechnology and Biological Sciences Research Council; Engineering and Physical Sciences Research Council; Medical Research Council; Wellcome Trust","keywords":"Telomere; Telomerase; Shelterin; Biology; Ribonucleoprotein; Cell biology; Telomerase RNA component; Telomerase reverse transcriptase; Senescence; DNA; Genetics; RNA; DNA-binding protein; Transcription factor; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002827791,0.0005606661,0.0005193675,0.0006171318,0.0007777769,0.00219065,0.0004288739,0.001050017,0.00708333],"category_scores_gemma":[0.0003630011,0.0002178832,0.0003628579,0.0004986806,0.00048074,0.001293939,0.001147879,0.001502753,0.003075586],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006823178,"about_ca_system_score_gemma":0.000626136,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003213327,"about_ca_topic_score_gemma":0.0003865853,"domain_scores_codex":[0.9996721,0.00004573271,0.00002293348,0.00007486454,0.0001319631,0.00005257321],"domain_scores_gemma":[0.9997906,0.00002789838,0.00004127882,0.00002006802,0.0000500772,0.00007018509],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.0004536365,0.00004483549,0.001637396,0.001549933,0.0001021071,0.001235862,0.0004926111,0.000602694,0.7641766,0.03758615,0.02559817,0.16652],"study_design_scores_gemma":[0.00005654273,0.000333833,0.005303538,0.0003763894,0.0001078483,0.002488223,0.0006126786,0.001063982,0.1510069,0.01649911,0.8220913,0.00005964134],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.1294884,0.7210647,0.05031646,0.01857311,0.006888644,0.0001533175,0.004048971,0.00265691,0.06680948],"genre_scores_gemma":[0.6341507,0.2772317,0.01355914,0.003099996,0.002887384,0.0001578239,0.003886817,0.000245318,0.06478108],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.00708333,"threshold_uncertainty_score":0.02369606,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01995877951791613,"score_gpt":0.2788860529699723,"score_spread":0.2589272734520562,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}