{"id":"W1963967290","doi":"10.1039/b309931h","title":"Integration of combined heteroduplex/restriction fragment length polymorphism analysis on an electrophoresis microchip for the detection of hereditary haemochromatosis","year":2004,"lang":"en","type":"article","venue":"The Analyst","topic":"Iron Metabolism and Disorders","field":"Medicine","cited_by":31,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Heteroduplex; Genotype; Restriction fragment length polymorphism; Biology; Genetics; Molecular biology; Restriction enzyme; Restriction digest; Mutant; Mutation; DNA; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003374351,0.0001459406,0.0003798386,0.0003576033,0.0001650032,0.000009762613,0.0001454005,0.00006735156,0.00001722546],"category_scores_gemma":[0.00005476562,0.00008248187,0.0003636502,0.001011558,0.00009377821,0.00005939502,0.00001182194,0.0001123978,0.000001718655],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005770014,"about_ca_system_score_gemma":0.00004153701,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002774379,"about_ca_topic_score_gemma":0.0006510403,"domain_scores_codex":[0.998888,0.00008664931,0.0003785955,0.0002023102,0.0002869095,0.000157546],"domain_scores_gemma":[0.9989305,0.0001013601,0.0002503447,0.0005436426,0.0001314023,0.00004279914],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002116292,0.000659571,0.0006988916,0.00006052342,0.0014488,0.00000113822,0.0007950316,0.004844062,0.9800209,0.0009293901,0.00009321971,0.008332113],"study_design_scores_gemma":[0.00295847,0.002216497,0.2004616,0.00003943337,0.01054347,0.000006324645,0.001856546,0.003829744,0.7770048,0.0008598182,0.000056627,0.0001665913],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9571462,0.0008529081,0.04053607,0.0008788337,0.00008105083,0.0004326555,0.00001993629,0.00001945557,0.00003286638],"genre_scores_gemma":[0.9989162,0.0003735487,0.0002666631,0.0001616795,0.0001007618,0.00003483966,0.0001024913,0.00001433201,0.00002947556],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2030161,"threshold_uncertainty_score":0.4194049,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01305789551999245,"score_gpt":0.2561280565017409,"score_spread":0.2430701609817484,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}