{"id":"W1963981640","doi":"10.4161/nucl.19232","title":"Chromatin signatures of active enhancers","year":2012,"lang":"en","type":"review","venue":"Nucleus","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":104,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canadian Nautical Research Society","funders":"Institut National de la Santé et de la Recherche Médicale; European Commission","keywords":"Enhancer; Chromatin; Biology; Histone; Computational biology; ChIA-PET; Enhancer RNAs; Promoter; Gene; Genetics; Regulation of gene expression; Genome; Gene expression; Chromatin remodeling","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003346938,0.0004703426,0.0007887325,0.001010996,0.0001534943,0.0007227503,0.0005289629,0.0007092414,0.001729436],"category_scores_gemma":[0.0003345037,0.0002402126,0.0002011315,0.0008148945,0.0006785664,0.0007327893,0.0005565754,0.0007904243,0.001594102],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005244729,"about_ca_system_score_gemma":0.0003697806,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003982514,"about_ca_topic_score_gemma":0.0005555501,"domain_scores_codex":[0.9998739,0.00001775793,0.00001063105,0.00004440604,0.00004071842,0.00001255171],"domain_scores_gemma":[0.9998696,0.00004943023,0.00002732792,0.000007807123,0.00003356965,0.00001228989],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001357663,0.00002741253,0.0009114729,0.01127627,0.00007928494,0.0005072369,0.0001889939,0.0006542549,0.07736746,0.0203074,0.01236986,0.8761744],"study_design_scores_gemma":[0.00001660603,0.00005628096,0.004868069,0.001728024,0.00008733691,0.00354442,0.0001169077,0.0001525219,0.02123663,0.007442216,0.9607172,0.00003371151],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001252002,0.9935447,0.001172167,0.0002647234,0.0001303971,0.000005504954,0.00008851037,0.00002580564,0.003516291],"genre_scores_gemma":[0.01168105,0.9837756,0.000957489,0.000317073,0.0001948396,0.00001366613,0.0001874467,0.000007522282,0.002865271],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001729436,"threshold_uncertainty_score":0.005785525,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01599613794547665,"score_gpt":0.2802522729908696,"score_spread":0.2642561350453929,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}