{"id":"W1963981640","doi":"10.4161/nucl.19232","title":"Chromatin signatures of active enhancers","year":2012,"lang":"en","type":"review","venue":"Nucleus","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":104,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canadian Nautical Research Society","funders":"Institut National de la Santé et de la Recherche Médicale; European Commission","keywords":"Enhancer; Chromatin; Biology; Histone; Computational biology; ChIA-PET; Enhancer RNAs; Promoter; Gene; Genetics; Regulation of gene expression; Genome; Gene expression; Chromatin remodeling","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007886788,0.0002771211,0.0006631371,0.00004474568,0.00003096606,0.000009345321,0.0003302089,0.0004969889,0.00006473799],"category_scores_gemma":[0.00001517429,0.0002410878,0.0003589185,0.00006869237,0.00006531164,0.000001442218,0.0001520266,0.0001619654,0.00002934719],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003640731,"about_ca_system_score_gemma":0.0001474664,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000007999028,"about_ca_topic_score_gemma":0.000009493397,"domain_scores_codex":[0.9990211,0.00005376873,0.0003270226,0.0002670069,0.00009881188,0.0002322508],"domain_scores_gemma":[0.999051,0.0000125637,0.0003900736,0.0004364438,0.00004253591,0.00006733038],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000005963269,0.00005182731,5.400939e-7,0.003387309,0.0002223228,6.177581e-7,0.00004437963,0.000002474704,0.006824501,0.00003895775,0.0004750361,0.9889461],"study_design_scores_gemma":[0.00008705417,0.00008101406,0.000007972322,0.0005762564,0.0003056096,0.000008667107,0.00001819881,0.000003251591,0.001838733,0.00001086658,0.9968019,0.0002605343],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.002115082,0.9939033,0.00002580149,0.000001572528,0.0002342821,0.0002634782,0.0002259031,0.000007559576,0.003222981],"genre_scores_gemma":[0.002643559,0.9952287,0.000940619,0.00001584351,0.0002933726,0.00002654556,0.0004644709,0.00006760097,0.0003192983],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9963268,"threshold_uncertainty_score":0.9831277,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01599613794547665,"score_gpt":0.2802522729908696,"score_spread":0.2642561350453929,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}