{"id":"W1964070553","doi":"10.1016/j.vetimm.2007.02.006","title":"Control of cytokine gene expression using small RNA interference: Blockade of interleukin-10 and interferon-gamma gene expression in pig cells","year":2007,"lang":"en","type":"article","venue":"Veterinary Immunology and Immunopathology","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Guelph","funders":"","keywords":"Biology; Molecular biology; RNA interference; Peripheral blood mononuclear cell; Gene expression; Messenger RNA; Cytokine; Concanavalin A; Interferon gamma; Interleukin 2; RNA; Gene; Immunology; Biochemistry; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004982561,0.0003225681,0.0005864007,0.0003108396,0.00006135282,0.000008279993,0.0003347744,0.0005162845,0.0000344233],"category_scores_gemma":[0.00005193736,0.0003039145,0.00008644039,0.00008968993,0.000627611,0.00001912363,0.0006012756,0.0002797472,0.000001830773],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002010376,"about_ca_system_score_gemma":0.00004239724,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000453161,"about_ca_topic_score_gemma":0.000009139176,"domain_scores_codex":[0.9978868,0.0002874973,0.0007977034,0.0005425363,0.00006023049,0.0004252116],"domain_scores_gemma":[0.9989112,0.00006478695,0.0003636221,0.0004899147,0.0001197681,0.00005071481],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.006322723,0.0001652065,0.002058113,0.00005202603,0.00006220327,0.00009493708,0.0003990799,0.000011083,0.9876806,0.000003259994,0.000004880467,0.003145882],"study_design_scores_gemma":[0.002071852,0.006574398,0.00774282,0.000207073,0.00002785581,0.0008916863,0.0003566621,0.0000373595,0.9816767,0.00002836224,0.0001301826,0.0002550324],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9834328,0.00705108,0.008833079,0.00001343214,0.0003549573,0.0002122986,0.00003859532,0.000008445404,0.00005536983],"genre_scores_gemma":[0.9958564,0.001451949,0.00244958,0.00004208613,0.00005231747,0.00001217847,0.00003962599,0.00002631206,0.00006956597],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01242364,"threshold_uncertainty_score":0.9999413,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01772801910963733,"score_gpt":0.2532245238388086,"score_spread":0.2354965047291713,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}