{"id":"W1964078930","doi":"10.1007/s11912-012-0285-1","title":"Custirsen (OGX-011): Clusterin Inhibitor in Metastatic Prostate Cancer","year":2012,"lang":"en","type":"review","venue":"Current Oncology Reports","topic":"Clusterin in disease pathology","field":"Medicine","cited_by":15,"is_retracted":false,"has_abstract":false,"ca_institutions":"London Health Sciences Centre; Western University","funders":"","keywords":"Clusterin; Prostate cancer; Medicine; Cancer; Cancer research; Radiation therapy; Prostate; Oncology; Metastasis; Disease; Internal medicine; Apoptosis; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003661746,0.0006511426,0.0009656708,0.00123349,0.0001773644,0.0005560133,0.0006011729,0.0005088028,0.002856847],"category_scores_gemma":[0.0003392552,0.0001835993,0.0003583944,0.001293979,0.000267191,0.0004396556,0.0004089861,0.001003209,0.00117259],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004915274,"about_ca_system_score_gemma":0.0007756715,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009530381,"about_ca_topic_score_gemma":0.002403226,"domain_scores_codex":[0.9999202,0.000012511,0.00001134625,0.00001425725,0.00002836594,0.00001326462],"domain_scores_gemma":[0.9998761,0.00003963687,0.0000334131,0.000003662242,0.00002169369,0.00002548343],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003896538,0.0001219074,0.0002969769,0.008153082,0.0001868332,0.0002905528,0.00002380115,0.0004176213,0.00307749,0.0008414412,0.04320753,0.942993],"study_design_scores_gemma":[0.0003810428,0.0007989244,0.002421157,0.001420541,0.0004948248,0.002388906,0.00003678167,0.0002378351,0.003162487,0.0004758624,0.9881521,0.00002950931],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001262815,0.9955707,0.0002377351,0.00039181,0.0002645748,0.00001913848,0.00007981071,0.00002856746,0.002144919],"genre_scores_gemma":[0.006760398,0.9890947,0.0003700305,0.0004843741,0.0002800186,0.00002747198,0.0002332748,0.000005030049,0.002744694],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002856847,"threshold_uncertainty_score":0.009557128,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2137405686444005,"score_gpt":0.4977886081882951,"score_spread":0.2840480395438946,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}