{"id":"W1964078930","doi":"10.1007/s11912-012-0285-1","title":"Custirsen (OGX-011): Clusterin Inhibitor in Metastatic Prostate Cancer","year":2012,"lang":"en","type":"review","venue":"Current Oncology Reports","topic":"Clusterin in disease pathology","field":"Medicine","cited_by":15,"is_retracted":false,"has_abstract":false,"ca_institutions":"London Health Sciences Centre; Western University","funders":"","keywords":"Clusterin; Prostate cancer; Medicine; Cancer; Cancer research; Radiation therapy; Prostate; Oncology; Metastasis; Disease; Internal medicine; Apoptosis; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001213279,0.0009233671,0.004786901,0.0007643267,0.00005985829,0.00001875098,0.0001924857,0.0006376167,0.0008146235],"category_scores_gemma":[0.0004071915,0.0007565127,0.0007215696,0.0005898916,0.0003572239,0.0001131983,0.0005865447,0.00162965,0.0002359133],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001942165,"about_ca_system_score_gemma":0.004383203,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000034613,"about_ca_topic_score_gemma":0.00009650525,"domain_scores_codex":[0.9937209,0.0007177304,0.00277568,0.001235572,0.0004293466,0.001120701],"domain_scores_gemma":[0.9958345,0.0002752149,0.001932508,0.001175215,0.0001679444,0.0006146127],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00005741217,0.001128005,0.002600881,0.04691038,0.0002212727,0.01162155,0.0002403269,0.000001164786,0.000001198585,0.000003570837,0.003162965,0.9340513],"study_design_scores_gemma":[0.0008320311,0.000220482,0.0005130385,0.01704342,0.005572677,0.01695737,0.00002208995,0.000003854775,6.41981e-7,0.00002256155,0.9583208,0.0004910612],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0005824845,0.982041,0.000005619169,0.0001393567,0.01106642,0.004733805,0.0001131645,0.0001291336,0.001189026],"genre_scores_gemma":[0.0002366716,0.9919308,0.0002263679,0.00008837121,0.001330843,0.004034454,0.0007291051,0.0001745201,0.001248871],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9551578,"threshold_uncertainty_score":0.9994886,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2137405686444005,"score_gpt":0.4977886081882951,"score_spread":0.2840480395438946,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}