{"id":"W1964079833","doi":"10.1073/pnas.072088099","title":"The procaspase-8 isoform, procaspase-8L, recruited to the BAP31 complex at the endoplasmic reticulum","year":2002,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Endoplasmic Reticulum Stress and Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":125,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"","keywords":"Endoplasmic reticulum; Cell biology; FADD; STIM1; Gene isoform; Caspase; Biology; Chemistry; Molecular biology; Apoptosis; Programmed cell death; Gene; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001423317,0.0002544845,0.0002415318,0.000167196,0.0003284552,0.0004187071,0.0001837255,0.0004145828,0.0008058129],"category_scores_gemma":[0.0002029181,0.0001610094,0.000218914,0.0001176202,0.0003001687,0.0005227964,0.0004447592,0.0006732636,0.0009037235],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004112077,"about_ca_system_score_gemma":0.0001399296,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001504116,"about_ca_topic_score_gemma":0.0002206358,"domain_scores_codex":[0.9998398,0.00002349746,0.00001461337,0.00004207914,0.00004816463,0.00003182613],"domain_scores_gemma":[0.9998251,0.00002361868,0.00003938372,0.00002977719,0.00003173698,0.00005058272],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002013033,0.000007060166,0.0001710863,0.00001544792,0.00000110461,0.0001672779,0.00001111162,0.00001607138,0.998804,0.00009995832,0.00002582484,0.0006609829],"study_design_scores_gemma":[0.000009133679,0.00006842496,0.003135054,0.000003830742,0.000003462768,0.001979133,0.00003150904,0.0004052056,0.990526,0.00009580073,0.003737831,0.000004732836],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9845558,0.002247059,0.01108113,0.0003487558,0.00004754452,0.00003202517,0.000166232,0.0001266852,0.001394719],"genre_scores_gemma":[0.9862905,0.001398346,0.007502479,0.0001155958,0.00002477102,0.00002701072,0.0005610227,0.00002482327,0.004055389],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008058129,"threshold_uncertainty_score":0.00298357,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04896238393030066,"score_gpt":0.2938735711143829,"score_spread":0.2449111871840823,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}