{"id":"W1964083798","doi":"10.1038/nm.2385","title":"Caspase 3–mediated stimulation of tumor cell repopulation during cancer radiotherapy","year":2011,"lang":"en","type":"article","venue":"Nature Medicine","topic":"Cell death mechanisms and regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":896,"is_retracted":false,"has_abstract":false,"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto; Ontario Institute for Cancer Research","funders":"National Institute of Dental and Craniofacial Research; National Cancer Institute","keywords":"Apoptosis; Cancer research; Programmed cell death; Cancer; Caspase; Biology; Radiation therapy; Cancer cell; Cytotoxic T cell; Caspase 3; Medicine; Internal medicine; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004404532,0.0004746708,0.000521182,0.0004009152,0.000263655,0.0004661972,0.0003264473,0.0005376903,0.003569103],"category_scores_gemma":[0.0003862639,0.0002319718,0.0007259225,0.0003637851,0.0003652974,0.0004408821,0.0002685781,0.001406989,0.000785493],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005673276,"about_ca_system_score_gemma":0.0003510493,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000446539,"about_ca_topic_score_gemma":0.0006037119,"domain_scores_codex":[0.9996181,0.00009864157,0.00002718774,0.00003899931,0.00007437822,0.0001427696],"domain_scores_gemma":[0.9997918,0.00007071986,0.00004954125,0.00003814498,0.00002176764,0.00002791632],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001555752,0.00008011764,0.00009437339,0.00008798236,0.00001709904,0.00008515718,0.00003372228,0.0002249656,0.9941388,0.0002467973,0.0001977969,0.003237351],"study_design_scores_gemma":[0.0000974333,0.0005070549,0.002734973,0.00001164251,0.00002495419,0.0003222293,0.0000296359,0.001236497,0.9935796,0.0001678804,0.001279035,0.000008944841],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9817392,0.008012984,0.005275561,0.0003645242,0.0001516544,0.0001097076,0.0005772403,0.0003360746,0.00343304],"genre_scores_gemma":[0.9955865,0.001098064,0.001195308,0.00008168472,0.00002242729,0.0000567387,0.0002744443,0.00003506448,0.001649676],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003569103,"threshold_uncertainty_score":0.01193982,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009036556026447927,"score_gpt":0.2569991915873737,"score_spread":0.2479626355609258,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}