{"id":"W1964126006","doi":"10.1007/s00018-009-0118-z","title":"Regulation of estrogen receptor beta activity and implications in health and disease","year":2009,"lang":"en","type":"review","venue":"Cellular and Molecular Life Sciences","topic":"Estrogen and related hormone effects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":70,"is_retracted":false,"has_abstract":false,"ca_institutions":"Agriculture and Agri-Food Canada","funders":"European Commission","keywords":"Estrogen receptor beta; Estrogen receptor alpha; BETA (programming language); Estrogen receptor; Estrogen; Receptor; Phytoestrogens; Biology; Estrogen-related receptor gamma; Endocrinology; Cell biology; Internal medicine; Genetics; Medicine; Cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005652274,0.000836337,0.001346553,0.00124272,0.0002243135,0.0008126674,0.0009091682,0.0009576912,0.002550182],"category_scores_gemma":[0.0005993231,0.0002869318,0.0002468996,0.001941411,0.0006040473,0.001024329,0.0006002408,0.001406312,0.001855781],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007225843,"about_ca_system_score_gemma":0.0008595397,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001229501,"about_ca_topic_score_gemma":0.002602706,"domain_scores_codex":[0.9998814,0.00001527411,0.00001643805,0.00002531966,0.00004840535,0.00001320102],"domain_scores_gemma":[0.9998235,0.00007797273,0.00002534027,0.00000668095,0.00004765396,0.00001880932],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001307432,0.00004791057,0.0002065719,0.005986263,0.00005419295,0.000320855,0.00004133156,0.0004143508,0.004457849,0.004223078,0.03048853,0.9536284],"study_design_scores_gemma":[0.00002625618,0.00005138333,0.001087369,0.0009824765,0.00007266092,0.00121882,0.00007236287,0.00007765587,0.0008227191,0.00284022,0.9927329,0.00001525812],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001327403,0.9983019,0.0001898021,0.000243106,0.0001952346,0.000002955828,0.00001737366,0.000005674798,0.0009113179],"genre_scores_gemma":[0.0007963791,0.9978404,0.000239774,0.0001594727,0.0001915059,0.000004837013,0.00002370164,0.000001143116,0.0007427266],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002550182,"threshold_uncertainty_score":0.008531213,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01750582996066609,"score_gpt":0.3027862569242377,"score_spread":0.2852804269635716,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}