{"id":"W1964171854","doi":"10.1006/taap.2001.9152","title":"Differential Effects of Trivalent and Pentavalent Arsenicals on Cell Proliferation and Cytokine Secretion in Normal Human Epidermal Keratinocytes","year":2001,"lang":"en","type":"article","venue":"Toxicology and Applied Pharmacology","topic":"Arsenic contamination and mitigation","field":"Environmental Science","cited_by":290,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Research Council Canada; Vedecká Grantová Agentúra MŠVVaŠ SR a SAV; Consejo Nacional de Ciencia y Tecnología; U.S. Environmental Protection Agency","keywords":"Viability assay; Arsenic; Cell growth; Chemistry; Arsenite; Arsenic toxicity; Glutathione; Biochemistry; Biology; Cell; Enzyme","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001274186,0.0001246121,0.0002030304,0.00006453314,0.000111181,0.000006244598,0.00003956218,0.0001208274,0.0009150485],"category_scores_gemma":[0.0000072373,0.0001198679,0.00001430812,0.00005702901,0.0002197962,0.00005921844,0.00008920944,0.0001492866,0.000005667134],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003688482,"about_ca_system_score_gemma":0.000005509306,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000009336898,"about_ca_topic_score_gemma":0.00005053176,"domain_scores_codex":[0.9990774,0.0001367323,0.0002535406,0.0002750351,0.00008093996,0.0001762928],"domain_scores_gemma":[0.9996054,0.0001640306,0.0001055477,0.00004829,0.000004073145,0.00007265715],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002649982,0.0003066316,0.02362671,0.00004175164,0.000008447139,0.00000865819,0.0005378756,0.00005504584,0.9616739,0.001099845,0.0001156153,0.01226048],"study_design_scores_gemma":[0.004612484,0.0005464733,0.474114,0.000006013231,0.00005076844,0.00002067606,0.00005606751,0.00187378,0.5180085,0.0002658069,0.0003014629,0.0001440211],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9971129,0.00002743137,0.0001709701,0.0003212831,0.00008119334,0.0006255534,0.000002025941,0.00001274064,0.00164591],"genre_scores_gemma":[0.9989716,0.000188456,0.00005590052,0.0004873263,0.00004150723,0.00008683243,0.00001528953,0.000005837463,0.0001472947],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4504873,"threshold_uncertainty_score":0.9999983,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008765803225160882,"score_gpt":0.2593273235214152,"score_spread":0.2505615202962543,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}