{"id":"W1964204750","doi":"10.1210/jc.2015-1551","title":"Prolonged Correction of Serum Phosphorus in Adults With X-Linked Hypophosphatemia Using Monthly Doses of KRN23","year":2015,"lang":"en","type":"article","venue":"The Journal of Clinical Endocrinology & Metabolism","topic":"Parathyroid Disorders and Treatments","field":"Medicine","cited_by":169,"is_retracted":false,"has_abstract":true,"ca_institutions":"Shriners Hospitals for Children - Canada","funders":"National Center for Advancing Translational Sciences; Kyowa Hakko Kirin","keywords":"Hypophosphatemia; Renal function; Internal medicine; Endocrinology; Medicine; Pi; Chemistry; Rickets; Osteomalacia; Vitamin D and neurology; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007569347,0.0003396249,0.0006058002,0.0001583314,0.0001895212,0.0001664433,0.0002132912,0.0002705927,0.0005783268],"category_scores_gemma":[0.001052167,0.0001017451,0.0001924668,0.0001530443,0.0002335944,0.0001913056,0.0001411978,0.0003901668,0.0001189075],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001807923,"about_ca_system_score_gemma":0.0002869334,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003386821,"about_ca_topic_score_gemma":0.0006907178,"domain_scores_codex":[0.9997347,0.0001290334,0.00002649007,0.00003829413,0.00004497844,0.00002656445],"domain_scores_gemma":[0.9995978,0.0001009138,0.0001377888,0.00002830022,0.00002486734,0.000110251],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.138157,0.01015735,0.2845528,0.000795253,0.0005346906,0.002077969,0.0008379975,0.002459146,0.1769902,0.0001481971,0.001605621,0.3816837],"study_design_scores_gemma":[0.02029894,0.4133627,0.5312476,0.00007130318,0.0003564762,0.006336118,0.0002216502,0.002249427,0.02176836,0.0001631919,0.003898145,0.00002615928],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9984514,0.001058975,0.0002245226,0.00003797023,0.00000531615,0.00003626231,0.0000224311,0.00001268316,0.0001505041],"genre_scores_gemma":[0.9988596,0.0003012537,0.0005962591,0.00004852654,0.00001948379,0.00004064242,0.00005766715,0.000001458209,0.00007499155],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007569347,"threshold_uncertainty_score":0.004003108,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06472566918885012,"score_gpt":0.3694696774561169,"score_spread":0.3047440082672668,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}