{"id":"W1964217351","doi":"10.1016/j.molmed.2008.11.003","title":"Ocular gene therapy: current progress and future prospects","year":2008,"lang":"en","type":"review","venue":"Trends in Molecular Medicine","topic":"Retinal Development and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":69,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Institute of Genetics","keywords":"Genetic enhancement; Gene transfer; Blinding; Blindness; Viral vector; Gene delivery; Medicine; Biology; Gene; Bioinformatics; Computational biology; Neuroscience; Clinical trial; Genetics; Optometry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001334182,0.0008303457,0.001572463,0.001120653,0.0002922208,0.001498246,0.0009894925,0.001558243,0.004211199],"category_scores_gemma":[0.0008067164,0.000213982,0.0004435619,0.001214349,0.0009580279,0.0019582,0.0005566215,0.002218565,0.00179336],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006641061,"about_ca_system_score_gemma":0.001079747,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007711286,"about_ca_topic_score_gemma":0.002243247,"domain_scores_codex":[0.9998218,0.00003023806,0.00002361316,0.00003849777,0.00006047488,0.00002538955],"domain_scores_gemma":[0.9994292,0.0003433097,0.00004781257,0.00001396967,0.0001046438,0.00006109445],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001853553,0.0001162358,0.0003304906,0.00550643,0.0000538634,0.0004319852,0.00005818742,0.0004934186,0.002509824,0.005821615,0.02732551,0.9571671],"study_design_scores_gemma":[0.000081876,0.0001704371,0.001007144,0.002232166,0.0001428684,0.002279792,0.0001482351,0.0002398585,0.001044002,0.004971602,0.9876529,0.00002912169],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002052202,0.9970829,0.0004454433,0.0007101325,0.0003521667,0.000003652509,0.00001008958,0.00001152862,0.001178917],"genre_scores_gemma":[0.001030524,0.9967647,0.0006243404,0.0004461955,0.0003791148,0.000008828195,0.0000206304,0.000002795865,0.0007229375],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.004211199,"threshold_uncertainty_score":0.0140878,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02188023923673483,"score_gpt":0.3352860680040565,"score_spread":0.3134058287673217,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}