{"id":"W1964329261","doi":"10.3816/ccc.2008.n.018","title":"A Four-Arm, Randomized, Multicenter Phase II Trial of Oxaliplatin Combined with Varying Schedules of 5-Fluorouracil as First-line Therapy in Previously Untreated Advanced Colorectal Cancer","year":2008,"lang":"en","type":"article","venue":"Clinical Colorectal Cancer","topic":"Colorectal Cancer Treatments and Studies","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":false,"ca_institutions":"Hôtel-Dieu de Montréal; Sunnybrook Health Science Centre","funders":"","keywords":"Oxaliplatin; Medicine; Fluorouracil; Colorectal cancer; Oncology; Internal medicine; Randomized controlled trial; Phases of clinical research; Bevacizumab; Cancer; Clinical trial; Chemotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0007626612,0.0006153361,0.003374882,0.0002066854,0.0002333464,0.000009289043,0.0002115727,0.000298009,0.000641326],"category_scores_gemma":[0.001295172,0.0004147954,0.0007031519,0.0007283142,0.001237627,0.0001667614,0.0001348857,0.0005614996,0.000003245256],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000376224,"about_ca_system_score_gemma":0.0009517792,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002046013,"about_ca_topic_score_gemma":0.002555689,"domain_scores_codex":[0.9953466,0.0003972609,0.002127214,0.0008167287,0.0006840975,0.0006281121],"domain_scores_gemma":[0.9954392,0.002215889,0.00105732,0.0003182404,0.0006926614,0.0002766874],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9069809,0.00857491,0.05308488,0.0001480661,0.001748448,0.0001564267,0.001274319,0.000181508,0.0008119248,0.00001983724,0.00005990097,0.02695888],"study_design_scores_gemma":[0.8733554,0.09617693,0.01228214,0.001010062,0.0006833212,0.00002217442,0.00009252141,0.001119115,0.01459577,0.00005166597,0.0001778918,0.0004330473],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9860719,0.004861045,0.00001021021,0.0008702201,0.0006592877,0.00656426,0.0001207389,0.0000762791,0.0007659889],"genre_scores_gemma":[0.9739162,0.02206568,0.0005567491,0.0002308716,0.0002388165,0.00266301,0.00004724203,0.00007265253,0.0002088222],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.08760202,"threshold_uncertainty_score":0.9998304,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06183287709231467,"score_gpt":0.383567008611192,"score_spread":0.3217341315188774,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}