{"id":"W1964329261","doi":"10.3816/ccc.2008.n.018","title":"A Four-Arm, Randomized, Multicenter Phase II Trial of Oxaliplatin Combined with Varying Schedules of 5-Fluorouracil as First-line Therapy in Previously Untreated Advanced Colorectal Cancer","year":2008,"lang":"en","type":"article","venue":"Clinical Colorectal Cancer","topic":"Colorectal Cancer Treatments and Studies","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":false,"ca_institutions":"Hôtel-Dieu de Montréal; Sunnybrook Health Science Centre","funders":"","keywords":"Oxaliplatin; Medicine; Fluorouracil; Colorectal cancer; Oncology; Internal medicine; Randomized controlled trial; Phases of clinical research; Bevacizumab; Cancer; Clinical trial; Chemotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003072941,0.002548492,0.004435403,0.001009644,0.0006671234,0.001382599,0.001743971,0.002158877,0.005420816],"category_scores_gemma":[0.002970357,0.001202194,0.001881631,0.0008182193,0.002327971,0.001848701,0.0007246092,0.004379994,0.0009908349],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001215396,"about_ca_system_score_gemma":0.001838154,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001700298,"about_ca_topic_score_gemma":0.003168172,"domain_scores_codex":[0.9988029,0.0006836098,0.00006321595,0.0001942055,0.00006720164,0.0001888965],"domain_scores_gemma":[0.9981384,0.0004691619,0.0003498628,0.0002182855,0.00009396514,0.0007302977],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9759259,0.01258659,0.0002895593,0.0001537926,0.0003473495,0.00001679821,0.00004649232,0.0003482839,0.002553241,0.00005589794,0.0003158027,0.00736029],"study_design_scores_gemma":[0.9342446,0.06433463,0.0005691693,0.000005983108,0.0001484791,0.00001215109,0.00001250725,0.0001869055,0.0002660638,0.00005023766,0.0001601913,0.000009217732],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9936519,0.001101154,0.0005007106,0.0005255289,0.0004089955,0.002243944,0.0004220119,0.0001027102,0.001042943],"genre_scores_gemma":[0.987016,0.001413745,0.002358032,0.001020496,0.0004353149,0.003274563,0.001179376,0.00005089441,0.003251668],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005420816,"threshold_uncertainty_score":0.01813442,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06183287709231467,"score_gpt":0.383567008611192,"score_spread":0.3217341315188774,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}