{"id":"W1964361634","doi":"10.1016/j.biomaterials.2015.03.018","title":"Newly identified interfibrillar collagen crosslinking suppresses cell proliferation and remodelling","year":2015,"lang":"en","type":"article","venue":"Biomaterials","topic":"Collagen: Extraction and Characterization","field":"Materials Science","cited_by":55,"is_retracted":false,"has_abstract":false,"ca_institutions":"Montreal General Hospital; Université Laval; Wilfrid Laurier University; McGill University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Copper; Ascorbic acid; Extracellular matrix; Type I collagen; Biophysics; Denaturation (fissile materials); Collagenase; Fibrillogenesis; Copper deficiency; Fibril; Cell growth; Biochemistry; Chemistry; Materials science; Biology; Endocrinology; Enzyme","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000232126,0.0004324391,0.0001942865,0.0003179332,0.0001810934,0.0002609143,0.000164454,0.0003534467,0.00149712],"category_scores_gemma":[0.0001755002,0.0001753246,0.0002484356,0.0001521855,0.0001738771,0.0001839943,0.000123481,0.0004645968,0.0002846742],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002059422,"about_ca_system_score_gemma":0.0001947606,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000161765,"about_ca_topic_score_gemma":0.0005763101,"domain_scores_codex":[0.9998475,0.0000286164,0.0000136267,0.00003846577,0.00003128011,0.00004051852],"domain_scores_gemma":[0.9997308,0.00006705347,0.00008253816,0.00002982565,0.00002662598,0.00006315717],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007411338,0.00001578218,0.00004593583,0.00001180754,0.000002626225,0.00001813068,0.00000253977,0.00001034947,0.999388,0.00001701418,0.000008378951,0.0004053732],"study_design_scores_gemma":[0.00001170225,0.0001207495,0.001258409,0.000002376981,0.00001369437,0.0001245531,0.00000501873,0.0001480316,0.9975625,0.00001143189,0.0007392308,0.000002293283],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9892552,0.002723615,0.005948842,0.0001088943,0.00006119305,0.00005478185,0.0003459085,0.00008276168,0.001418803],"genre_scores_gemma":[0.9895784,0.001016732,0.005734394,0.0001196138,0.00003766044,0.00004152783,0.0005712282,0.00003735001,0.002863219],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00149712,"threshold_uncertainty_score":0.00500834,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03952878643393324,"score_gpt":0.2641037822445037,"score_spread":0.2245749958105705,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}